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Description
Finasteride is a synthetic steroidal compound belonging to the 4-azasteroid class, widely recognised in endocrinology research and in the biochemistry of androgen hormones. In this catalogue the material is supplied as a pharmaceutical research reagent for experimental laboratory use only, and not as a finished medicine or any preparation intended for human administration. Its principal role is that of a 5-alpha-reductase inhibitor, acting on the enzyme that catalyses the conversion of testosterone into dihydrotestosterone, which makes the compound an important molecular tool for researchers investigating androgen signalling pathways across a range of cell and tissue models.
The properties that make this material a preferred choice are its selectivity and its mechanism of action, which have been studied in depth over several decades, so that its profile of activity can serve as a dependable reference point in experimental design. As an inhibitor with clearly defined behaviour toward its target enzyme, finasteride is frequently employed as a positive control in enzyme activity assays as well as in cell-based assays. Its rigid and highly specific steroidal framework also makes it an attractive reference structure for molecular modelling work and for structure-activity relationship studies.
In Indonesian laboratories, this reagent is typically used within academic, university and institutional research settings where androgen metabolism and hormone biochemistry are under study. It suits work carried out in biochemistry, pharmacology and molecular biology laboratories that require a well-characterised enzyme inhibitor for experimental purposes. Users should note that the material is intended strictly for research and experimental applications in a controlled laboratory environment, and it is handled by trained personnel following the institution's standard operating procedures.
Laboratory Applications
5-Alpha-Reductase Inhibition Assays: the compound acts directly on the enzyme that converts testosterone to dihydrotestosterone, making it the natural choice for probing this catalytic step.
Androgen Signalling Pathway Studies: because it intervenes at a defined point in androgen metabolism, it allows researchers to dissect downstream signalling events in cell and tissue models.
Positive Control in Enzyme Activity Assays: its clearly characterised inhibitory behaviour toward the target enzyme provides a dependable benchmark against which experimental samples can be compared.
Cell-Based Assay Controls: the same well-documented mechanism makes it suitable as a reference inhibitor in cellular systems where androgen-dependent responses are being measured.
Molecular Modelling and Structure-Activity Relationship Studies: its rigid, highly specific steroidal architecture makes it an informative reference scaffold for computational docking work and comparative structural analysis.
Specifications
Brand: TCI
Catalogue number: F0675
CAS number: 98319-26-7
Category: Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents (for Experimental Use)
Pack sizes: available in the pack sizes listed on this product page
Storage: refer to the manufacturer's label and accompanying documentation for the recommended storage conditions
Handling and Storage
Store the material in its original, tightly closed container under the conditions indicated on the manufacturer's label, keeping it away from direct sunlight, moisture and sources of heat or ignition. Suitable containers include the supplied primary packaging or clean, chemically compatible glass or plastic vessels that are clearly labelled with the product identity. Handle the reagent in a well-ventilated area or within a fume hood, wearing appropriate personal protective equipment such as gloves, safety glasses and a laboratory coat. Avoid inhalation of dust and direct contact with skin or eyes, and refrain from eating or drinking in the handling area. This material is intended for experimental laboratory use by trained personnel only, and all handling, use and disposal should follow the institution's standard operating procedures together with the safety data sheet supplied with the product.
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