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TCI

CAS 140-10-3

trans-Cinnamic Acid [Matrix for MALDI-TOF/MS] TCI C3412

trans-Cinnamic Acid [Matrix for MALDI-TOF/MS] TCI C3412

Chemical Identity

Other names
trans-3-Phenylacrylic Acid
CAS No.
140-10-3
PubChem
CID 444539·SID 354335755
Formula
C9H8O2
Molecular weight
148.16 g/mol
Purity
>99.5%(GC)(T)
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(E)-3-phenylprop-2-enoic acid
SMILES
C1=CC=C(C=C1)C=CC(=O)O
InChIKey
WBYWAXJHAXSJNI-VOTSOKGWSA-N
MDL
MDL00004369
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Trans-Cinnamic Acid (TCI C3412) is a chemical compound widely used in analytical chemistry, particularly in mass spectrometry techniques. It serves as a matrix for MALDI-TOF/MS, a powerful analytical method that enables the identification and precise measurement of molecular masses. In the laboratory, this compound plays a crucial role in facilitating the ionization of target molecules, making it easier to detect and analyze complex chemical components. Its application is essential in various research fields where high-resolution mass analysis is required.

The chemical properties of Trans-Cinnamic Acid make it a preferred choice for MALDI-TOF/MS applications. It exhibits chemical stability and the ability to form well-defined crystals, which are critical for effective matrix performance. Additionally, it has a high molecular affinity for a wide range of organic compounds, enhancing ionization efficiency and improving measurement sensitivity. These characteristics ensure reliable and reproducible results, making it a popular choice among analytical chemists.

In Indonesian laboratories, Trans-Cinnamic Acid is extensively used in chemical analysis research, particularly in higher education institutions and research organizations. It supports studies in analytical chemistry, biochemistry, and pharmaceutical sciences. Its versatility and reliability make it an essential reagent for researchers working on molecular characterization and structural analysis.

  • Mass Spectrometry Analysis – Trans-Cinnamic Acid is ideal for MALDI-TOF/MS due to its ability to facilitate ionization of large molecules, making it suitable for protein and peptide analysis.
  • Biochemical Research – The compound supports the analysis of biomolecules, aiding in the study of complex biological systems and molecular interactions.
  • Pharmaceutical Development – It is used in the characterization of drug compounds, helping to determine molecular structures and purity levels.
  • Environmental Analysis – Trans-Cinnamic Acid assists in the detection of organic pollutants in environmental samples, providing accurate mass measurements.
  • Forensic Science – It is employed in the identification of trace organic compounds, supporting forensic investigations and analytical case studies.

Brand TCI
CAS number 140-10-3
Molecular formula —
Purity —
Category Analytical Chemistry > Analytical Reagents > Mass Spectrometry (MS) Reagents
Pack sizes Available in various quantities as per standard reagent packaging
Physical form Solid, crystalline powder
Storage Store in a cool, dry place away from direct sunlight

Trans-Cinnamic Acid should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is recommended to keep the compound in a sealed container to avoid moisture absorption and contamination. Due to its crystalline nature, it should be handled with care to prevent physical damage. In a laboratory setting, it is advisable to use gloves and appropriate safety equipment when handling the material. The compound is generally non-hazardous but should be stored away from incompatible substances. Proper storage ensures the reagent remains effective for analytical applications.

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