3,3-Dimethylglutarimide TCI D1324

Chemical Identity

Other names: 4,4-Dimethyl-2,6-piperidinedione
CAS No.: 1123-40-6
PubChem: CID 14292·SID 87567844
Formula: C7H11NO2
Molecular weight: 141.17 g/mol
Purity: >98.0%(GC)(qNMR)
Reference databases: ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 4,4-dimethylpiperidine-2,6-dione
SMILES: CC1(CC(=O)NC(=O)C1)C
InChIKey: YUJCWMGBRDBPDL-UHFFFAOYSA-N
MDL: MDL00006671

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Dokumen Keamanan & Mutu

↓ Unduh SDS / MSDS (PDF resmi TCI)

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3,3-Dimethylglutarimide is a six-membered cyclic imide, specifically a piperidine-2,6-dione ring that carries two methyl groups at position 3 (position 4 under piperidine numbering). The compound can be prepared from 3,3-dimethylglutarate and is a valuable building block in organic synthesis laboratories. Its imide N–H group is mildly acidic and can be alkylated or acylated, and its two carbonyl groups can be reduced or ring-opened. A single starting material can therefore be taken in many synthetic directions, which gives it a useful place on the shelf of any synthesis group.

Researchers are interested in this compound because the glutarimide scaffold appears in many bioactive molecules and is an important motif in modern medicinal chemistry. The gem-dimethyl substitution adds conformational rigidity. It also blocks that position from unwanted enolization, so reactions at the nitrogen atom or the carbonyl groups proceed in a more controlled way. Because it is a relatively stable solid, the material is easy to weigh, store, and handle in routine laboratory work. Supplied under the TCI brand, it gives chemists a consistent source of this scaffold for multi-step synthetic programs.

In Indonesia, 3,3-Dimethylglutarimide is useful to medicinal chemistry and organic synthesis laboratories at universities, research institutes, and pharmaceutical companies that are developing imide-derived compounds. Academic groups can use it in teaching and research on heterocycle construction and functional group transformations. Industrial research teams can use it as a starting point when exploring glutarimide-containing candidate structures. AMI Scientific supplies this TCI product to laboratories that need a dependable building block for synthesis projects that run from exploratory route scouting to systematic derivative preparation.

Related TCI products

N-alkylation and N-acylation studies: the mildly acidic imide N–H lets chemists add a wide range of substituents on nitrogen to build libraries of new imide derivatives.
Carbonyl reduction and ring-opening chemistry: the two carbonyl groups can be reduced or ring-opened, so one material leads to several structurally different intermediates for further synthesis.
Medicinal chemistry scaffold development: the glutarimide core appears in many bioactive molecules, which makes this compound a relevant starting point for designing and preparing candidate structures.
Controlled-reactivity synthesis: the gem-dimethyl group blocks unwanted enolization at that position, so transformations at nitrogen or the carbonyls are more selective and easier to predict.
Teaching and academic research in organic synthesis: as a relatively stable, easy-to-handle solid, it suits university laboratories that demonstrate imide reactivity and functional group interconversions.

Brand	TCI (product code D1324)
CAS number	1123-40-6
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes	available in TCI standard pack sizes; please confirm the current options with AMI Scientific
Physical form	relatively stable solid
Storage	keep in a tightly closed container according to the manufacturer's label and Safety Data Sheet

Store 3,3-Dimethylglutarimide in its original, tightly sealed container in a cool, dry, well-ventilated area, away from moisture, heat sources, and incompatible chemicals. Follow the storage conditions on the TCI label and Safety Data Sheet. Reseal the container promptly after each use so the material stays in good condition. When handling, wear standard laboratory protective equipment, including safety glasses, gloves, and a lab coat. Weigh and transfer the solid in a fume hood or another ventilated area to avoid inhaling dust, and avoid contact with skin and eyes. Clean up spills promptly and dispose of waste according to local regulations and your institution's chemical safety procedures.

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