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Description
TCI D1360 4-Allyl-1,2-dimethoxybenzene, commonly known as methyl eugenol, is an aromatic compound built on a benzene ring bearing two adjacent methoxy groups and a single allyl side chain. Within the non-heterocyclic building block category, this compound serves a dual role: as a starting material for organic synthesis that carries a reactive allyl group, and as an important reference compound in essential oil analysis. Its phenylpropanoid-derived structure means the material appears frequently in natural product chemistry studies, aroma research, and the development of more advanced aromatic derivatives in the laboratory.
The characteristics that make this compound a preferred choice begin with the terminal double bond on the allyl chain, which is readily manipulated through isomerisation, oxidation, epoxidation, hydroboration, and metathesis reactions. At the same time, the two methoxy groups on the ring are electron-donating, so they direct aromatic substitution reactions toward specific positions and simplify the design of targeted derivatives. The liquid form with its characteristic aroma makes volumetric handling straightforward, and the reagent-grade quality supplied by TCI makes it suitable as a reference material in chromatographic analysis. This combination of functional groups allows a single molecule to support several different synthetic routes.
In Indonesian laboratories, this compound is typically encountered in university research groups and institutional facilities working on natural product chemistry, particularly those studying essential oils and their aromatic constituents. It is also used in synthetic organic chemistry laboratories that prepare aromatic derivatives, and in analytical laboratories that require a well-characterised comparison compound when identifying components by chromatography. The reagent-grade quality supports both teaching-scale synthetic work and more demanding research applications.
Laboratory Applications
- Essential oil analysis — serves as a comparison compound for identifying methyl eugenol in chromatographic separations, where a reagent-grade reference is needed for reliable peak assignment.
- Organic synthesis starting material — the reactive allyl group provides a handle for building more complex aromatic structures through a range of established transformation routes.
- Allyl group transformation studies — the terminal double bond readily undergoes isomerisation, oxidation, epoxidation, hydroboration, and metathesis, making it useful for exploring each of these reaction classes.
- Aromatic substitution chemistry — the two electron-donating methoxy groups direct incoming substituents to specific ring positions, allowing researchers to design derivatives with predictable regiochemistry.
- Natural product and aroma chemistry research — as a phenylpropanoid derivative, it supports studies of naturally occurring aromatic compounds and the fragrance properties associated with this structural class.
Specifications
- Brand: TCI
- CAS Number: 93-15-2
- Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
- Product Code: D1360
- Physical Form: liquid with a characteristic aroma
- Pack Sizes: available in standard TCI reagent packaging; please confirm the required size when ordering
- Storage: store according to the conditions stated on the manufacturer's label
Handling and Storage
Store this reagent in a cool, well-ventilated area away from direct sunlight, heat sources, and ignition sources, following the conditions stated on the manufacturer's label. Keep the material in its original tightly closed container, or in a compatible chemically resistant bottle if transferred, and label any secondary container clearly. Because the product is a liquid with a characteristic aroma, handle and dispense it inside a fume hood to limit vapour exposure. Wear appropriate personal protective equipment, including safety glasses, gloves, and a laboratory coat. Avoid contact with strong oxidising agents, keep containers closed when not in use to preserve reagent quality for analytical work, and consult the manufacturer's safety data sheet before first use and for disposal guidance.
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