Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 4-5 minggu setelah pembayaran.
Couldn't load pickup availability
Description
TCI D3898 Di-tert-butyl L-(+)-Tartrate is the di-tert-butyl ester of L-tartaric acid, a naturally occurring chiral compound bearing two adjacent stereogenic centres and two secondary hydroxyl groups. It belongs to the family of chiral building blocks — materials that supply stereochemical information to a target molecule so that the final product can be obtained as a single enantiomer. In asymmetric synthesis laboratories, tartrate derivatives serve as chiral auxiliaries, as ligands for metal catalysts, and as diol protecting groups that control the direction from which a reagent approaches the substrate.
The characteristic that makes this compound stand out is the combination of the optical purity of a natural product with the steric bulk of the tert-butyl group. The tartrate framework provides C2 symmetry, which is highly useful because it reduces the number of possible transition states and therefore significantly improves reaction selectivity. The bulky tert-butyl ester groups reinforce facial differentiation of the molecule while also being more resistant to nucleophilic attack and basic conditions than the corresponding methyl or ethyl esters. A further advantage is that the tert-butyl groups can be removed under comparatively mild acidic conditions without damaging the stereogenic centres.
In Indonesian laboratories, this material is typically found in university and institutional research groups working on asymmetric synthesis, organic methodology development, and the preparation of enantiomerically enriched intermediates. It is generally used at bench scale in synthesis and organic chemistry laboratories, where a defined, reliably supplied chiral starting material is required for reproducible stereoselective work, method validation, and postgraduate research projects.
Laboratory Applications
Chiral auxiliary in stereoselective synthesis — the C2-symmetric tartrate backbone limits the accessible transition states, so reagents approach the substrate from a single preferred face.
Ligand precursor for metal catalysts — the two adjacent secondary hydroxyl groups provide defined coordination points that transfer stereochemical information from the natural tartrate skeleton to the metal centre.
Diol protecting group chemistry — the tartrate unit can mask a diol while simultaneously directing the geometry of subsequent transformations on the remaining reactive positions of the molecule.
Preparation of enantiomerically enriched intermediates — the optical purity inherited from natural L-tartaric acid allows target molecules to be obtained as a single enantiomer rather than a racemate.
Methodology development in asymmetric synthesis research — the bulky tert-butyl esters resist nucleophilic attack and basic conditions, letting researchers explore reaction conditions that would cleave methyl or ethyl esters.
Specifications
Brand: TCI
CAS number: 117384-45-9
Catalogue code: D3898
Category: Chemistry > Asymmetric Synthesis > Chiral Building Blocks
Chemical class: di-tert-butyl ester of L-(+)-tartaric acid; chiral building block with two stereogenic centres and two secondary hydroxyl groups
Pack sizes and storage conditions: as supplied by the manufacturer; please refer to the manufacturer's product label and Safety Data Sheet
Handling and Storage
Store the container tightly closed in a cool, dry, well-ventilated place away from direct sunlight, heat sources, moisture, and strong acids or bases, following the storage conditions stated on the manufacturer's label and Safety Data Sheet. Keep the material in its original supplier container, or in a clean, chemically compatible, well-sealed glass container that is clearly labelled with the product name, CAS number, and date of opening. Handle in a fume hood using appropriate personal protective equipment — safety glasses, gloves, and a laboratory coat. Because the tert-butyl ester groups are sensitive to acidic conditions, avoid contact with acids during storage and weighing to preserve the integrity of the stereogenic centres. Review the Safety Data Sheet before first use and dispose of residues through the laboratory's chemical waste procedure.
