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Description
TCI D4198 Dimethylamine, CAS 124-40-3, is supplied as a ready-to-use solution in isopropyl alcohol at a concentration of approximately 11 percent, or roughly 2 mol per liter. Dimethylamine is the simplest secondary amine and ranks among the most frequently used non-heterocyclic building blocks in organic synthesis, particularly for introducing the dimethylamino group into a target molecule. Because the pure compound is a gas at room temperature, providing it as a solution makes the reagent far easier to measure, transfer, and handle in everyday laboratory work.
The principal advantage of this preparation lies in its convenience and dosing accuracy. With a defined concentration, researchers can calculate the molar quantity of reagent directly from the volume withdrawn using a syringe or pipette, without needing to handle pressurised gas or dedicated gas-handling equipment. Isopropyl alcohol as the solvent offers good solubility for many organic substrates and evaporates relatively easily during the final work-up stage. Dimethylamine itself is a strong nucleophile and an effective base, so it reacts rapidly across a range of carbon–nitrogen bond-forming transformations.
In Indonesian laboratories, this solution form fits naturally into university research groups, industrial R&D units, and analytical or synthetic service laboratories that prepare intermediates on a bench scale. It allows a workflow based on standard syringes, septum-capped flasks, and ordinary glassware rather than specialised gas lines. The predefined concentration also simplifies protocol documentation and repeatability across different operators and student cohorts.
Laboratory Applications
- Introduction of the dimethylamino group: the defined molar concentration lets chemists deliver an exact reagent charge by volume, supporting reproducible functionalisation of a target molecule.
- Carbon–nitrogen bond formation: dimethylamine acts as a strong nucleophile and reacts rapidly in bond-forming transformations, making this solution a practical amine source for routine synthetic steps.
- Non-heterocyclic building block synthesis: as one of the most frequently used building blocks in organic synthesis, it serves as a starting point for constructing more elaborate molecular frameworks.
- Bench-scale intermediate preparation: the isopropyl alcohol medium dissolves many organic substrates well and evaporates readily, so intermediates can be isolated without complicated solvent removal steps.
- Teaching and method development work: handling a liquid solution instead of a pressurised gas allows students and method developers to work safely with ordinary syringes, pipettes, and standard laboratory glassware.
Specifications
- Brand: TCI
- CAS number: 124-40-3
- Product code: D4198
- Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
- Physical form: solution in isopropyl alcohol, approximately 11 percent (approximately 2 mol/L)
- Pack sizes: please refer to the manufacturer's listing for available packaging options
- Storage: keep tightly sealed in the original container, away from heat and ignition sources
Handling and Storage
Store the container tightly closed in a cool, well-ventilated area, away from heat, sparks, and open flames, since the isopropyl alcohol solvent is flammable. Keep the reagent in its original manufacturer's packaging or in compatible, chemically resistant glassware fitted with a secure closure or septum, and avoid prolonged exposure to air. Dispense in a fume hood using a clean, dry syringe or pipette, and close the container immediately after withdrawal to limit solvent evaporation and reagent loss. Wear appropriate personal protective equipment, including safety goggles, chemical-resistant gloves, and a laboratory coat. Segregate the material from strong oxidising agents and acids, and follow the manufacturer's safety data sheet together with your institution's chemical handling and waste disposal procedures.
