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Description
TCI D4355, 1-(Dimethylamino)-3-[2-(3-methoxyphenethyl)phenoxy]-2-propanol Hydrochloride, is a complex organic compound built on an aryloxypropanolamine framework, a structural motif that is very well recognised in medicinal chemistry. The molecule consists of a phenoxy core carrying a methoxy-substituted phenethyl chain, connected to a propanol chain terminating in a dimethylamino group, and it is supplied as the hydrochloride salt. In the laboratory, compounds of this level of complexity generally serve as analytical reference materials, as intermediates in synthesis research, or as test substances in studies of the relationship between structure and activity within the aryloxypropanolamine class of compounds.
The property that makes this compound valuable is the completeness of its structural framework. The 1-amino-3-aryloxy-2-propanol motif presents a secondary hydroxyl group, a tertiary amine, and an aryl ether linkage within a single molecule, a combination that is difficult to construct from scratch and that normally demands several synthetic steps. The hydrochloride salt form offers practical advantages: a solid that is easier to handle, good solubility in aqueous media, and better storage stability compared with the corresponding free base. Together, these characteristics make the material a convenient starting point rather than a synthesis project in itself.
In Indonesian laboratories, a material of this kind is typically used in university research groups, pharmaceutical development laboratories, and analytical service laboratories that work on aryloxypropanolamine chemistry. It is generally ordered for a defined research programme — a synthesis route that requires a fully assembled framework, a method that requires a reference substance, or a structure-activity study that requires a well-characterised member of this compound class — rather than being kept as a routine bulk consumable on the general chemical shelf.
Laboratory Applications
- Analytical reference material — the defined structure and salt form make it suitable as a comparison substance when identifying or confirming aryloxypropanolamine-type compounds in analytical work.
- Synthesis intermediate — the assembled aryloxypropanolamine framework lets research chemists begin from a complete core instead of building the multi-step skeleton from simpler starting materials.
- Structure-activity relationship studies — as a well-defined member of the aryloxypropanolamine class, it serves as a test substance when comparing how structural variations affect measured activity.
- Method development work — its secondary hydroxyl, tertiary amine, and aryl ether groups within one molecule make it a useful probe substance when developing separation or detection methods.
- Functional group chemistry research — the combination of three distinct reactive handles in a single molecule supports selective derivatisation studies and comparative reactivity investigations in academic laboratories.
Specifications
- Brand: TCI (Tokyo Chemical Industry)
- CAS number: 135261-74-4
- Chemical name: 1-(Dimethylamino)-3-[2-(3-methoxyphenethyl)phenoxy]-2-propanol Hydrochloride
- Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
- Chemical form: hydrochloride salt, supplied in solid form
- Pack sizes: available in the research-scale pack sizes listed on the product page
Handling and Storage
Store the container tightly closed in a cool, dry place, protected from direct sunlight and away from sources of heat or moisture. Keep the material in its original supplier container, or in a clean, well-sealed amber glass container that is clearly labelled with the compound name and CAS number. Handle the solid in a fume hood or in a well-ventilated area to avoid inhaling dust, and wear standard laboratory personal protective equipment, including safety glasses, a laboratory coat, and chemically resistant gloves. Avoid contact with skin and eyes, and avoid generating dust when weighing. Always consult the manufacturer's Safety Data Sheet before use, and follow local institutional procedures for waste collection and disposal.
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![1-(Dimethylamino)-3-[2-(3-methoxyphenethyl)phenoxy]-2-propanol Hydrochloride (CAS 135261-74-4) - TCI D4355 - AMI Scientific](http://amiscientific.com/cdn/shop/files/TCI2510D4355.jpg?v=1768818078&width=1445)
