TCI
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Description
TCI D5681 4-Dodecylphenol is an alkylphenol compound that carries a twelve-carbon dodecyl chain at the para position relative to the phenolic hydroxyl group. The material belongs to the family of non-heterocyclic building blocks and serves in the laboratory as a starting material for preparing surfactants, resins, antioxidants, and a broad range of long-tailed phenol derivatives. Beyond synthetic work, the compound is widely used as a reference material in environmental and toxicological research, because alkylphenols form a class of compounds whose presence is routinely monitored in wastewater as well as in receiving water bodies.
The defining characteristic of this material is its amphiphilic nature, combining a water-loving hydroxyl group with a long, water-repelling alkyl chain. That pairing makes the compound an ideal base skeleton for the synthesis of nonionic surfactants through ethoxylation reactions. The long alkyl chain also increases solubility in organic solvents and lowers the tendency to volatilize, so handling in the laboratory is comparatively straightforward. Because substitution occupies the para position, the two ortho positions remain open, leaving room for directed introduction of new groups in phenol chemistry.
In Indonesian laboratories, 4-Dodecylphenol is typically stocked by university and institutional research groups working on surfactant development, polymer and resin formulation, and antioxidant chemistry, as well as by environmental laboratories that require alkylphenol reference materials for water and wastewater monitoring programmes. It is generally purchased in research-scale quantities for method development, comparative studies, and small-batch synthesis rather than for production use, and it is normally stored alongside other organic building blocks in a dedicated chemical store.
Laboratory Applications
- Nonionic surfactant synthesis — the amphiphilic structure provides a ready-made hydrophobic tail and reactive hydroxyl group, making it a direct precursor for ethoxylation into nonionic surfactant products.
- Resin and polymer preparation — the phenolic hydroxyl group participates in condensation chemistry while the long dodecyl chain imparts flexibility and organic-phase compatibility to the resulting resin systems.
- Antioxidant intermediate chemistry — the hindered phenol motif combined with a long alkyl tail is a common starting point for building oil-soluble antioxidant additives in laboratory-scale studies.
- Environmental reference material — alkylphenols are routinely monitored in wastewater and receiving waters, so this compound serves as a comparison standard during analytical method development and validation work.
- Toxicological research studies — as a representative member of the alkylphenol class, it is used as a comparison substance in investigations examining the behaviour and effects of this compound group.
- Directed phenol functionalisation — with the para position already substituted, the two free ortho positions allow controlled introduction of additional substituents for targeted derivative synthesis.
Specifications
- Brand: TCI
- CAS Number: 104-43-8
- Product Code: D5681
- Category: Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
- Pack sizes: available in standard research-scale laboratory pack sizes; please refer to the packaging options listed for this item
- Storage: keep in a tightly closed original container, protected from light, in a cool and well-ventilated chemical store
Handling and Storage
Store 4-Dodecylphenol in its original tightly closed container in a cool, dry, well-ventilated area away from heat sources, direct sunlight, and strong oxidising agents. Amber glass or the manufacturer's supplied container is suitable for keeping the material protected from light and moisture. Handle the compound inside a fume hood and wear appropriate personal protective equipment, including chemical-resistant gloves, safety glasses, and a laboratory coat. Avoid direct skin and eye contact as well as inhalation of vapours or aerosols. Because alkylphenols are environmentally monitored substances, avoid discharge to drains and collect residues and rinsings as chemical waste for proper disposal. Always consult the manufacturer's safety data sheet before use.
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