TCI
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Description
1,2-Bis(maleimido)ethane is a chemical compound widely used in biochemical and organic chemistry applications within laboratories. It serves as a key linker and crosslinker, enabling the formation of covalent bonds between molecules. This property makes it essential for various experimental processes that require molecular connectivity. Its role is critical in facilitating chemical reactions that involve interactions between different molecular species, such as proteins, nucleic acids, and other biomolecules. Due to its versatility, it is a fundamental component in many research protocols, supporting both basic and applied scientific investigations.
The compound’s unique molecular structure and high reactivity contribute to its popularity among researchers. Its symmetric structure allows for efficient crosslinking, while its ability to form stable covalent bonds through reaction with amino groups enhances its utility. These characteristics make it a preferred choice for applications requiring reliable and predictable chemical interactions. Additionally, its chemical stability under specific conditions ensures consistent performance in laboratory settings. This combination of reactivity and stability makes it a reliable reagent for a wide range of experimental needs.
In Indonesian laboratories, 1,2-Bis(maleimido)ethane is extensively used in biochemical, pharmaceutical, and organic chemistry research. It is commonly found in academic institutions and research centers where molecular connectivity is essential. Its application spans from basic research to the development of complex molecular structures, supporting both academic and industrial scientific endeavors. Its widespread use underscores its importance in advancing scientific knowledge and innovation in the region.
Laboratory Applications
- Bioconjugation applications benefit from its ability to form stable covalent bonds with amino groups, enabling precise molecular linking.
- Crosslinking experiments rely on its capacity to create crosslinks between biomolecules, enhancing structural integrity in molecular assemblies.
- Protein labeling studies utilize its reactivity to attach functional groups to proteins, aiding in structural and functional analysis.
- Nucleic acid modification processes take advantage of its crosslinking properties to create stable molecular linkages in DNA and RNA structures.
- Organic synthesis projects use its versatile reactivity to facilitate the construction of complex molecular frameworks in synthetic chemistry.
Specifications
- Brand: TCI
- CAS number: 5132-30-9
- Category: Chemistry > Chemical Biology > Linkers and Crosslinkers
- Pack sizes: Available in various quantities as per supplier specifications
- Physical form: Solid or powder, depending on the specific product variant
- Storage note: Store in a cool, dry place away from direct sunlight and moisture
Handling and Storage
The compound should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to moisture and air, which may affect its reactivity. Proper labeling of storage containers is essential for safety and traceability. In laboratory settings, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to minimize direct contact. Due to its reactivity, it should be stored separately from incompatible substances to avoid potential chemical interactions. Regular monitoring of storage conditions ensures the compound remains suitable for use in experimental applications.
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