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Description
TCI E1435, bearing CAS number 29806-73-3, is 2-Ethylhexyl Palmitate, an ester formed between sixteen-carbon palmitic acid and the branched alcohol 2-ethylhexanol. The compound belongs to the lipid class and is widely recognised in formulation work as an emollient, a material that imparts a soft, smooth feel to topical preparations. In the laboratory, however, its role extends well beyond cosmetic function: it serves as a model lipid, as the oil phase in the preparation of emulsions and nanoemulsions, and as a reference material in the chromatographic analysis of fatty acid esters.
The property that makes this ester such a frequent choice is the branching within its alcohol portion. A branched chain lowers the tendency of the molecules to pack into an ordered arrangement, so the material remains a liquid and pours easily at room temperature, in contrast to straight-chain palmitic acid esters, which tend to solidify. Its nonpolar character, its stability towards hydrolysis under neutral conditions, and its very faint odour together make it an unobtrusive carrier when it is used to dissolve lipophilic active substances.
From the standpoint of practical laboratory work, this clear liquid of moderate viscosity is easy to handle on the bench. Indonesian laboratories encounter it most often in pharmaceutical and cosmetic formulation groups developing topical and emulsion systems, in analytical laboratories preparing fatty acid ester standards, and in academic research settings where a stable, low-odour oil phase is needed for teaching and method development involving lipid systems.
Laboratory Applications
Emulsion and nanoemulsion preparation: the compound provides a stable, low-odour oil phase that remains liquid at room temperature, simplifying the dispersion and homogenisation steps of formulation trials.
Model lipid studies: as a well-defined fatty acid ester, it offers a representative and reproducible lipid system for investigating solubilisation, partitioning, and the general behaviour of nonpolar phases.
Chromatographic reference material: it serves as a reference substance in the analysis of fatty acid esters, supporting the identification and confirmation of ester peaks during method work.
Emollient formulation development: its characteristic soft, smooth feel on application makes it a standard choice when developing and evaluating topical preparations at laboratory scale.
Carrier for lipophilic actives: the nonpolar character and stability against hydrolysis under neutral conditions allow it to dissolve lipophilic substances without interfering with the active material.
Specifications
Brand: TCI
Catalogue reference: E1435
CAS number: 29806-73-3
Category: Life Science > Biochemicals and Reagents > Lipids
Physical form: clear liquid of moderate viscosity at room temperature, with a very faint odour
Pack sizes: available in standard laboratory pack sizes; please confirm the currently offered options when ordering
Storage: keep in a tightly closed container under the conditions indicated on the manufacturer's label
Handling and Storage
Store the material in a tightly closed container, kept in a cool, dry and well-ventilated area away from direct sunlight and sources of heat or ignition. Containers of glass or another chemically compatible material are suitable, and bottles should be closed immediately after dispensing to limit exposure to air and moisture. Handle the liquid in a well-ventilated space using standard laboratory personal protective equipment, including safety glasses, gloves and a laboratory coat. Avoid contact with skin and eyes, and clean any spilled liquid promptly, as the oily residue can leave surfaces slippery. Always consult the manufacturer's safety data sheet before use.
