N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine TCI F0926

Chemical Identity

Other names: N-Fmoc-L-propargylglycine · Fmoc-propargyl-Gly-OH · (S)-2-(Fmoc-amino)-4-pentynoic Acid
CAS No.: 198561-07-8
PubChem: CID 2734461·SID 253661677
Formula: C20H17NO4
Molecular weight: 335.36 g/mol
Purity: >98.0%(HPLC)(T)
Storage: 0-10°C

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pent-4-ynoic acid
SMILES: C#CCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
InChIKey: DJGMNCKHNMRKFM-SFHVURJKSA-N
MDL: MDL01075095

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N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine is a chemical compound widely used in biochemical experiments, particularly in conjugation chemistry and click chemistry applications. This compound plays a crucial role in laboratory settings where precise and efficient chemical reactions are required. Its unique molecular structure enables it to participate in specific and selective reactions, making it an essential tool for researchers working in biomedicine and pharmacology. It is commonly used as a building block for the synthesis of complex molecules with potential applications in drug development and biological research.

The compound's chemical properties make it a preferred choice in laboratory environments. It exhibits stability under certain conditions but is sensitive to moisture and oxidation, which necessitates careful handling. Its ability to react with various ligands, such as amines and hydroxyl groups, expands its applicability in biological chemistry reactions. These characteristics allow it to be a versatile reagent in experiments that require high specificity and efficiency. Its structural versatility also supports its use in a wide range of chemical modifications and conjugation processes.

In Indonesian laboratories, this compound is frequently utilized by researchers in universities and research institutions. It is integral to experiments involving molecular modification and the development of new compounds. Its availability through AMI Scientific ensures that Indonesian scientists have access to this essential reagent for their research needs. The compound's role in advancing scientific discovery in the region is significant, supporting both academic and applied research efforts.

TCI brochures (PDF)

Click Chemistry 2026-09-08 · p. 14
Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 21

Related TCI products

Used in Click Chemistry for efficient and selective bioconjugation reactions due to its reactive propargyl group and stable fluorenyl moiety.
Applied in drug development for synthesizing complex molecules with targeted biological activities through conjugation chemistry.
Utilized in molecular modification experiments to create functionalized compounds for biomedical applications.
Employed in pharmacological research to study the interaction of ligands with biological targets through chemical conjugation.
Integrated into biotechnology projects for the development of novel therapeutic agents through chemical synthesis and modification.

Brand	TCI
CAS number	198561-07-8
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Conjugation Chemistry/Click Chemistry
Pack sizes	Available in various quantities as per standard laboratory requirements
Physical form	Solid powder
Storage	Store in a dry, cool, and dark place away from moisture and oxidizing agents

This compound should be stored in a dry, cool, and dark environment to prevent degradation due to moisture and oxidation. It is recommended to use airtight containers made of glass or polyethylene to minimize exposure to humidity. Laboratory personnel should wear appropriate personal protective equipment, such as gloves and safety goggles, when handling the compound to ensure safety. The compound should be kept away from incompatible substances like strong acids or bases. Regular monitoring of storage conditions is advised to maintain its chemical integrity and effectiveness for research applications. Proper labeling of containers is essential to avoid accidental exposure and ensure safe handling in laboratory settings.

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