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TCI

CAS 77284-32-3

Fmoc-Nle-OH TCI F1324

Fmoc-Nle-OH TCI F1324

Chemical Identity

Other names
Fmoc-L-norleucine · N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-norleucine · (S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]hexanoic Acid
CAS No.
77284-32-3
PubChem
CID 7009636
Formula
C21H23NO4
Molecular weight
353.42 g/mol
Purity
>98.0%(HPLC)(T)
Reference databases
ChemSpider
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
SMILES
CCCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
InChIKey
VCFCFPNRQDANPN-IBGZPJMESA-N
MDL
MDL00037537
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TCI F1324 77284-32-3 Fmoc-Nle-OH is a chemical compound widely used in peptide synthesis, particularly in solid-phase peptide synthesis techniques. This compound plays a crucial role in the construction of complex peptide chains, which are essential for biochemical and pharmacological research. In laboratory settings, it serves as a key building block for creating peptides with specific structural characteristics. Its application extends to drug development, protein research, and biological analysis, making it a versatile tool for scientists working in various fields of chemistry and biology.

The compound is preferred due to its chemical reactivity and specificity, which enable efficient and controlled reactions during synthesis. The Fmoc (9-fluorenylmethyloxycarbonyl) group provides stability during the initial stages of peptide synthesis, while the Nle (Norleucine) amino acid residue adds structural diversity. These properties make it ideal for generating peptides with precise sequences and functional groups. Additionally, its reactivity allows for easy coupling and cleavage reactions, enhancing the efficiency of the synthesis process.

In Indonesian laboratories, Fmoc-Nle-OH is commonly used in chemical and molecular biology research. It is a popular choice due to its availability, quality, and ease of use across various experimental scales. Researchers in educational institutions and research organizations rely on this compound for its reliability and effectiveness in producing high-quality peptides for their studies.

TCI brochures (PDF)

  • Solid-phase peptide synthesis where Fmoc-Nle-OH serves as a protected amino acid for sequential peptide chain construction.
  • Drug development projects requiring the synthesis of peptides with specific amino acid sequences for therapeutic applications.
  • Biochemical research involving the study of protein structures and interactions using custom-designed peptides.
  • Molecular biology experiments that require the production of peptides for use in assays or as tools for functional studies.
  • Analytical chemistry applications where peptides are used for biomarker detection or as standards in mass spectrometry analyses.

Brand TCI
CAS number 77284-32-3
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes Available in various quantities as per standard laboratory supply options
Physical form Solid powder
Storage Store in a cool, dry place away from light and moisture

This compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical integrity. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. When handling, ensure proper laboratory safety protocols are followed, including the use of gloves and protective eyewear. Avoid inhalation of powder particles and ensure adequate ventilation in the workspace. The compound is not hazardous under normal storage conditions but should be treated with care during synthesis procedures to prevent accidental contamination or exposure. Always follow standard laboratory safety practices when working with chemical reagents.

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