Galunisertib TCI G0639

Chemical Identity

Other names: LY-2157299 · 4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide
CAS No.: 700874-72-2
Formula: C22H19N5O
Molecular weight: 369.43 g/mol
Purity: >98.0%(HPLC)(T)
Storage: 0-10°C

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 4-[2-(6-methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide
SMILES: CC1=NC(=CC=C1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N
InChIKey: IVRXNBXKWIJUQB-UHFFFAOYSA-N
MDL: MDL12923319
PubChem: CID 10090485

Rp 7.182.000,00

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Galunisertib is a chemical compound widely used in cancer research within the field of cell biology. It functions as a kinase inhibitor, playing a crucial role in laboratory settings by targeting specific signaling pathways involved in cancer cell proliferation and metastasis. This compound is essential for studying the molecular mechanisms underlying oncological diseases and for evaluating the efficacy of new cancer therapies. Its precise mechanism of action allows researchers to investigate the role of specific protein kinases in tumor development and progression.

One of the key attributes that make Galunisertib a preferred choice in laboratories is its high specificity and stability under controlled conditions. These properties ensure that experimental results are reliable and reproducible, making it ideal for high-precision research. Additionally, its ability to selectively inhibit certain signaling pathways enhances its utility in understanding complex biological processes. The compound's chemical stability also simplifies storage and handling, contributing to its widespread use in both academic and industrial research environments.

In Indonesian laboratories, Galunisertib is commonly used in cancer-related studies conducted by research institutions and universities. It is particularly favored for its accuracy and reliability in experimental setups that require precise control over biological pathways. Its application supports both fundamental research and applied studies aimed at developing new therapeutic strategies for cancer treatment. The compound's consistent performance in various experimental conditions further solidifies its position as a valuable tool in oncological research.

Cancer Cell Proliferation Studies: Galunisertib is used to inhibit specific kinases involved in cancer cell growth, helping researchers understand the molecular mechanisms of tumor development.
Metastasis Research: This compound targets signaling pathways that promote cancer cell migration and invasion, making it ideal for studying metastatic processes.
Drug Efficacy Testing: Galunisertib is employed to evaluate the effectiveness of new cancer drugs by blocking key signaling pathways that drive tumor progression.
Protein Kinase Function Analysis: Its high specificity allows researchers to investigate the role of individual protein kinases in oncogenic processes with precision.
Signal Transduction Pathway Investigations: Galunisertib enables the study of how specific signaling cascades contribute to cancer progression and treatment resistance.

Brand	TCI
CAS number	700874-72-2
Molecular formula	—
Purity	—
Category	Life Science > Cell Biology > Cancer Research
Pack sizes	Available in various quantities as per supplier specifications
Physical form	Solid (as per standard chemical properties)
Storage	Store in a cool, dry place away from light and moisture

Galunisertib should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent contamination and degradation. In laboratory settings, proper personal protective equipment (PPE) such as gloves and safety goggles should be worn when handling the compound to ensure safety. The substance should be kept in a designated chemical storage area that is accessible only to authorized personnel. Regular monitoring of storage conditions is advised to ensure optimal preservation and safe handling of the material.

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