1,2-Hexanediol TCI H0688

Chemical Identity

Other names: 1,2-Dihydroxyhexane · 1,2-Hexylene Glycol
CAS No.: 6920-22-5
PubChem: CID 94335·SID 87571060
Formula: C6H14O2
Molecular weight: 118.18 g/mol
Purity: >96.0%(GC)
Reference databases: ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: hexane-1,2-diol
SMILES: CCCCC(CO)O
InChIKey: FHKSXSQHXQEMOK-UHFFFAOYSA-N
MDL: MDL00010737

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1,2-Hexanediol from TCI (product code H0688) is a six-carbon aliphatic diol with two adjacent hydroxyl groups on the first and second carbon atoms. Its structure pairs a hydrophilic part, the two OH groups, with a lipophilic hydrocarbon chain, which makes the molecule mildly amphiphilic. In the laboratory, 1,2-hexanediol serves as a non-heterocyclic building block for organic synthesis, as a co-solvent, and as a test material in formulation research, especially in cosmetics and personal care products.

Its amphiphilic character is the main reason researchers choose 1,2-hexanediol. The compound can help dissolve ingredients that are poorly soluble in water. It also works as a humectant that retains moisture, and it is known to boost preservative systems in formulations. For synthetic chemists, the vicinal diol group is easy to modify: it can be converted into cyclic acetals or ketals, oxidized, or selectively esterified. Because it is a liquid at room temperature, it is easy to measure by volume, which fits its availability in millilitre-based pack sizes.

In Indonesia, 1,2-hexanediol is widely sought by cosmetic research and development laboratories, a sector that is expanding quickly alongside the domestic personal care industry. Formulation teams use it to test solubility, moisture retention, and preservative performance in prototype products. University chemistry laboratories and academic research groups also use it as a versatile diol building block for organic synthesis coursework and studies that explore reactions of vicinal hydroxyl groups.

Related TCI products

Cosmetic formulation research: its mild amphiphilic character lets formulators study how poorly water-soluble ingredients behave and dissolve in water-based prototype systems.
Preservative system studies: because it is known to boost preservative systems, researchers can use it to evaluate and optimize preservative performance in personal care formulations.
Humectant evaluation: its two hydroxyl groups help retain moisture, so it suits experiments that measure hydration and moisture retention in skin care prototypes.
Organic synthesis building block: its vicinal diol group can be converted into cyclic acetals or ketals, oxidized, or selectively esterified, which gives synthetic chemists several routes to new compounds.
Co-solvent applications: its combined hydrophilic and lipophilic structure makes it a useful auxiliary solvent when a single solvent cannot dissolve every component in a laboratory mixture.

Brand	TCI (product code H0688)
CAS number	6920-22-5
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes	millilitre-based pack sizes, suited to volumetric dispensing
Physical form	liquid at room temperature
Storage	keep tightly closed in a cool, dry, well-ventilated place; follow the manufacturer's label and Safety Data Sheet

Store 1,2-hexanediol in its original, tightly sealed container in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and strong oxidizing agents. Because the compound attracts moisture, close the container promptly after each use. If you transfer it, use clean, dry, chemically compatible glass or suitable plastic containers with clear labels. Handle it with standard laboratory precautions: wear safety glasses, chemical-resistant gloves, and a lab coat, and avoid contact with the eyes and skin. Dispense measured volumes using clean pipettes or graduated cylinders. Always check the manufacturer's Safety Data Sheet for specific hazard information, and dispose of waste according to local regulations.

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