1-(2-Hydroxyethyl)-3-methylimidazolium Chloride TCI H1254

TCI H1254 with CAS number 61755-34-8 is 1-(2-Hydroxyethyl)-3-methylimidazolium Chloride, an ionic liquid from the imidazolium family that carries a functional hydroxyl group on its side chain. The compound consists of a positively charged imidazolium cation paired with a chloride anion, forming an organic salt with a low melting point that falls within the specialty synthesis category. In the laboratory, ionic liquids of this type are used as alternative solvents replacing volatile organic solvents, as reaction media, and at the same time as catalysts or co-catalysts in a wide range of chemical transformations.

What distinguishes this compound from ordinary ionic liquids is the presence of a hydroxyl group that can serve a dual function. That group allows the ionic liquid to act as a hydrogen bond donor, which improves its ability to dissolve polar compounds such as cellulose and other carbohydrates, while also providing an anchoring point when the ionic liquid is to be immobilised on a solid support. The chloride anion is known for its strong coordinating ability, making it highly effective at disrupting the hydrogen bonding network of biopolymers. Very low vapour pressure and good thermal stability round out the profile of this ionic liquid.

In Indonesian laboratories, this material is typically handled in university research groups, biomass and lignocellulose processing laboratories, and industrial R&D units working on green chemistry approaches. It is generally used at bench scale, where the ionic liquid serves as a reaction medium or dissolution agent in method development work before any decision is made about scaling up. Its non-volatile character also makes it attractive for facilities seeking to reduce their dependence on conventional volatile organic solvents.

• Alternative green solvent systems — replaces volatile organic solvents in reaction work, since its very low vapour pressure limits solvent evaporation and reduces the release of organic vapour into the laboratory atmosphere.
• Cellulose and carbohydrate dissolution — the strongly coordinating chloride anion breaks the extensive hydrogen bonding network holding biopolymer chains together, allowing polar carbohydrate materials to be brought into solution.
• Reaction medium for organic synthesis — functions as a low melting organic salt that dissolves polar substrates and can be held at elevated temperature thanks to its good thermal stability.
• Catalysis and co-catalysis — the imidazolium cation together with the pendant hydroxyl group can participate directly in chemical transformations, letting the liquid act as both medium and catalytic component simultaneously.
• Supported ionic liquid phase preparation — the hydroxyl group provides a chemical anchoring point for grafting or immobilising the ionic liquid onto solid supports used in heterogeneous systems.

• Chemical name: 1-(2-Hydroxyethyl)-3-methylimidazolium Chloride

Store the container tightly closed in a cool, dry, well ventilated area away from moisture, since imidazolium chloride salts are generally hygroscopic and readily pick up atmospheric water. Keep the material in its original supplier container or in a compatible tightly sealed glass vessel, and reseal promptly after each withdrawal. Handle in a fume hood using gloves, safety glasses, and a laboratory coat, transferring with clean dry implements to avoid contamination. Consult the manufacturer's safety data sheet before first use, and dispose of residues and contaminated material through the laboratory's chemical waste stream rather than the drain.

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