Hygromycin B TCI H1509

Chemical Identity

CAS No.: 31282-04-9
Formula: C20H37N3O13
Molecular weight: 527.5 g/mol
Purity: >80.0%(HPLC)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (3'R,3aS,4S,4'S,5'R,6R,6'R,7S,7aS)-4-[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy-6'-[(1S)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol
SMILES: CN[C@H]1C[C@H]([C@@H]([C@H]([C@@H]1O)O[C@H]2[C@@H]3[C@H]([C@H]([C@H](O2)CO)O)OC4(O3)[C@@H]([C@H]([C@H]([C@H](O4)[C@H](CO)N)O)O)O)O)N
InChIKey: GRRNUXAQVGOGFE-HUCHGKBZSA-N
PubChem: CID 56928061

Rp 955.500,00

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Berat 200mg 1g

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Hygromycin B is a biochemical compound widely used in molecular biology and pharmacology experiments. It plays a crucial role in laboratory settings by inhibiting cell growth, particularly in cells with high proliferative activity. As a selective agent, it is essential for selecting cells resistant to antibiotics, enabling researchers to isolate cells with specific genetic traits. Its ability to suppress protein synthesis makes it a valuable tool in genetic studies and gene expression analysis.

This compound is favored for its chemical stability under certain conditions and its strong antimicrobial activity against a variety of bacteria and fungi. Its effectiveness in inhibiting protein synthesis further enhances its utility in research applications. Additionally, Hygromycin B is compatible with various cell culture media, both liquid and solid, making it versatile for different experimental setups. Its reliability and consistent performance contribute to its widespread use in scientific research.

In Indonesian laboratories, Hygromycin B is commonly used in biomedical and biotechnology research. It is integral to experiments requiring cell selection, toxicity testing, and studies on cellular responses to environmental factors. Its availability in the local market supports ongoing research efforts, ensuring that scientists have access to this essential reagent for their work.

Molecular biology experiments where cell growth inhibition is required for studying genetic traits.
Antibiotic resistance selection processes to isolate genetically modified or resistant cell lines.
Protein synthesis inhibition studies to investigate gene expression and cellular function.
Toxicity testing to evaluate the impact of various compounds on cell viability and function.
Cell culture media preparation for maintaining and manipulating cell lines in biotechnology applications.

Brand	TCI
CAS number	31282-04-9
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Glycoscience
Pack sizes	Available in standard laboratory quantities as per supplier specifications
Physical form	Powder or solution, depending on product formulation
Storage	Store in a cool, dry place away from direct sunlight and moisture

Hygromycin B should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep the compound in airtight containers to prevent exposure to moisture and contaminants. Due to its antimicrobial properties, it is important to handle the substance with care to avoid cross-contamination in the laboratory. Always use appropriate personal protective equipment, such as gloves and safety goggles, when handling this reagent. Proper labeling of storage containers is essential to ensure safe handling and prevent accidental misuse. Regular monitoring of storage conditions helps maintain the integrity and effectiveness of the compound for research applications.

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