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Description
Fradiomycin Sulfate, supplied under TCI catalogue code F0649, is the sulfate salt form of fradiomycin, an aminoglycoside antibiotic more widely known by the name neomycin. As an aminoglycoside compound, its molecule is built from amino sugar units linked to one another through glycosidic bonds, which places this material squarely within the scientific domain of glycoscience. In the laboratory, it serves as a reference antibacterial agent as well as a research material for studying how antibiotics act upon the bacterial ribosome.
The characteristics that make this material a preferred choice are its broad spectrum of activity against bacteria, particularly Gram-negative bacteria, together with its distinctive mechanism of action: binding to the bacterial ribosomal subunit and disrupting the fidelity of protein translation. The sulfate salt form is chosen because it offers good solubility in water and far more practical handling than the free base form. That high water solubility makes it straightforward to prepare stock solutions for addition to culture media or for sensitivity testing work.
In Indonesian laboratories, this material is typically used wherever a dependable reference antibacterial agent is required, including microbiology work involving culture media supplementation and antibiotic sensitivity testing. Its ready dissolution in water suits routine stock solution preparation, while its role as a study material for ribosome-targeted antibiotic action makes it relevant to academic and research settings examining aminoglycoside behaviour within the wider context of glycoscience.
Laboratory Applications
Antibacterial reference agent — its broad activity spectrum against bacteria makes it a dependable comparator material when antibacterial behaviour must be assessed against a known aminoglycoside standard.
Antibiotic sensitivity testing — high water solubility allows stock solutions to be prepared and dispensed conveniently for sensitivity work without the handling difficulties associated with the free base form.
Culture media supplementation — the sulfate salt dissolves readily in water, so it can be introduced into culture media from an aqueous stock solution with practical and repeatable handling.
Ribosome-targeted antibiotic research — it binds the bacterial ribosomal subunit and disrupts protein translation fidelity, giving researchers a well-defined tool for studying that mechanism of action.
Glycoscience study material — its molecule consists of amino sugar units joined through glycosidic bonds, making it a relevant subject for research concerned with aminoglycoside structure and function.
Specifications
Brand: TCI
CAS number: 1405-10-3
Category: Chemistry > Chemical Biology > Glycoscience
Chemical form: sulfate salt of fradiomycin (neomycin), an aminoglycoside antibiotic
Solubility: good solubility in water
Pack sizes: available in the pack sizes listed on this product page
Storage note: hygroscopic material; keep tightly closed and protected from moisture
Handling and Storage
As is generally the case with aminoglycoside salts, this material is hygroscopic and readily absorbs water vapour from the surrounding air. It should therefore be kept in a tightly closed container and protected from atmospheric moisture, with the container allowed to reach ambient temperature before opening so that condensation does not form on the contents. Weighing and transfer are best carried out promptly, using clean, dry spatulas and dry glass or suitable plastic containers, and the container should be resealed immediately after use. Handle the material as an antibiotic substance, using standard laboratory personal protective equipment such as gloves, safety glasses and a laboratory coat, working in a well-ventilated area, avoiding the generation and inhalation of dust, and washing hands thoroughly after handling.
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