Sitagliptin phosphate TCI I1231 is a chemical compound widely used in pharmaceutical research and biochemical studies. As a DPP-4 inhibitor, it plays a crucial role in modulating the activity of GLP-1, a hormone essential for glucose regulation. This compound is essential for experimental work in laboratories focusing on diabetes research and metabolic disorders. Its application extends to the development and testing of new therapeutic agents, making it a key reagent in the field of experimental pharmacology.
The compound is chemically stable and highly soluble in organic solvents such as ethyl acetate and acetone, which makes it suitable for various analytical techniques like HPLC and spectroscopy. Its phosphate group allows for interactions with enzymes and proteins, enhancing its utility in biochemical assays. These properties ensure consistent performance and reliability in laboratory settings, making it a preferred choice for researchers.
In Indonesian laboratories, sitagliptin phosphate is commonly used by scientists in pharmacology, biochemistry, and health sciences. It is frequently found in research institutions and universities working on diabetes-related studies and drug development. Its role in experimental research underscores its importance in advancing scientific understanding and therapeutic innovation in the region.
- Diabetes research and glucose regulation studies benefit from sitagliptin phosphate's ability to modulate GLP-1 activity, aiding in the development of new therapeutic strategies for type 2 diabetes.
- Pharmaceutical research applications rely on its role as a DPP-4 inhibitor, enabling the study of enzyme activity and drug interactions in metabolic pathways.
- Biochemical assays utilize its solubility and stability to ensure accurate and reproducible results in analytical techniques such as HPLC and spectroscopy.
- Drug development projects incorporate this compound to evaluate the efficacy and mechanism of action of potential therapeutic agents in experimental models.
- Enzyme and protein interaction studies take advantage of its phosphate group, allowing for the investigation of molecular interactions in biomedicine and pharmacology.
| Brand | TCI |
|---|---|
| CAS number | 654671-78-0 |
| Molecular formula | — |
| Purity | — |
| Category | Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents |
| Pack sizes | — |
| Physical form | — |
| Storage | Store in a cool, dry place away from moisture and light |
Sitagliptin phosphate should be stored in a cool, dry place, away from moisture and direct light to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to air and humidity, which could affect its integrity. In laboratory settings, it is important to handle the compound with care, using appropriate personal protective equipment such as gloves and safety goggles. While it is not classified as hazardous under standard conditions, proper handling procedures should be followed to ensure safety during experimentation. The compound should be kept in a secure location, away from incompatible materials to prevent any potential chemical interactions. Regular monitoring of storage conditions is advised to maintain the quality and effectiveness of the reagent for research purposes.
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