Lenalidomide is a chemical compound widely utilized in pharmaceutical research and drug development, particularly in the field of proteolysis targeting chimera (PROTAC) research. This compound plays a crucial role in the development of molecules capable of facilitating the degradation of target proteins through mechanisms distinct from traditional enzyme inhibition. In laboratory settings, lenalidomide serves as a key reagent for exploring molecular interactions and the mechanisms of action of new therapeutic agents. Its versatility makes it an essential tool for researchers aiming to advance drug discovery and understand complex biological processes.
Lenalidomide is valued for its chemical stability and solubility in specific organic solvents, which simplifies chemical manipulation and experimental procedures. These properties ensure consistent performance across various experimental conditions, making it a preferred choice for high-precision applications in synthesis and clinical testing. Additionally, its well-documented biological activity enhances its relevance in drug development and biomedical research. The compound’s specificity and reliability contribute to its widespread use in both academic and industrial research environments.
In Indonesian laboratories, lenalidomide is commonly used by pharmacologists and chemists for the development of new drugs, toxicity testing, and research into disease mechanisms. Its application supports efforts to improve the quality and innovation of local research, aligning with global advancements in pharmaceutical science. This compound is integral to the work of researchers aiming to contribute to the development of novel therapeutic solutions.
- Drug development and PROTAC research due to its ability to facilitate protein degradation through novel mechanisms.
- Molecular interaction studies as it enables the investigation of protein-protein and protein-ligand interactions.
- Toxicity testing as it supports the evaluation of compound safety and biological effects in experimental models.
- Disease mechanism research for understanding the role of specific proteins in pathological conditions.
- Synthesis of new therapeutic agents due to its chemical stability and compatibility with various reaction conditions.
| Brand | TCI |
|---|---|
| CAS number | 191732-72-6 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Pharmaceutical Development and Drug Discovery Research Reagents > Proteolysis Targeting Chimera Research Reagents |
| Pack sizes | Available in standard laboratory quantities as per supplier specifications |
| Physical form | Solid powder (as per standard product description) |
| Storage | Store in a cool, dry place away from light and moisture |
Lenalidomide should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent exposure to air and humidity, which could affect its integrity. Due to its chemical nature, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Proper labeling of containers is essential for safe handling and to prevent accidental contamination. Regular monitoring of storage conditions is advised to ensure the compound remains suitable for use in research applications. Always follow standard laboratory safety protocols when working with this reagent.
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