2'-O-Methyluridine TCI M2290

2'-O-Methyluridine is a synthetic nucleotide compound widely used in chemical biology and biotechnology research. It plays a crucial role in laboratory settings where the synthesis and modification of nucleic acids such as RNA and DNA are required. This compound is essential for the development of oligonucleotides, vaccine research, and studies on transcription and translation mechanisms. Its stability and structural similarity to natural uridine make it a valuable tool in various scientific investigations.

The unique chemical properties of 2'-O-Methyluridine make it a preferred choice for researchers. The methyl substitution at the 2' hydroxyl group of the ribose sugar provides enhanced resistance to enzymatic degradation, particularly by RNase. This stability ensures the compound remains active in biological environments for extended periods. Additionally, its non-immunogenic nature makes it safe for use in medical and pharmaceutical research, reducing potential complications in experimental outcomes.

In Indonesian laboratories, 2'-O-Methyluridine is commonly used in molecular biology and biochemistry research. It is a key component in the development of synthetic nucleic acids and is frequently employed in academic and industrial research settings. Its reliability and compatibility with various laboratory techniques make it a standard material for nucleic acid-related experiments.

• Synthesis of modified RNA and DNA molecules due to its structural similarity to natural nucleotides and resistance to enzymatic degradation.
• Development of vaccines and therapeutic oligonucleotides because of its stability and non-immunogenic properties.
• Study of transcription and translation mechanisms as it mimics natural nucleotides and can be incorporated into RNA structures.
• Production of oligonucleotides for gene therapy and diagnostic applications due to its chemical stability and ease of manipulation.
• Research in molecular biology and biotechnology for applications requiring precise nucleic acid modification and stability.

2'-O-Methyluridine should be stored in a cool, dry place, away from direct light and moisture. It is recommended to use airtight containers to prevent contamination and maintain its chemical integrity. Due to its stability, it does not require refrigeration but should be handled with care to avoid exposure to extreme temperatures. In laboratory settings, it is advisable to use gloves and proper ventilation when handling the compound to ensure safety and maintain experimental accuracy. Always follow standard laboratory safety protocols to prevent any potential risks during handling and storage.

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