2'-O-Methylguanosine is a chemical compound widely used in biochemical and molecular biology experiments. It serves as a crucial component in the synthesis of RNA and DNA, playing a vital role in research related to the structure and function of nucleic acids. In the laboratory, it functions as a building block for the creation of oligonucleotides, RNA modifications, and studies on protein-RNA interactions. Its unique chemical structure enables it to participate in various biochemical reactions and synthetic processes, making it an essential reagent for nucleic acid chemistry.
The compound's stability and controlled reactivity make it a preferred choice for researchers. The presence of a methyl group at the 2' position enhances its chemical stability compared to regular guanosine, thereby extending reaction times and reducing degradation. This characteristic ensures consistent results in experimental settings, which is critical for reliable scientific outcomes. Additionally, its ability to interact with a wide range of biological molecules makes it versatile for multiple applications in molecular biology and chemical synthesis.
In Indonesian laboratories, 2'-O-Methylguanosine is extensively used in biomedical, pharmacological, and biotechnology research. It is commonly found in experiments involving RNA synthesis, gene modification, and drug development. Its availability in the local market supports ongoing scientific investigations, enabling researchers to conduct high-quality experiments without the need for international sourcing.
- RNA synthesis and modification experiments benefit from 2'-O-Methylguanosine due to its stability and compatibility with nucleic acid chemistry.
- Gene modification studies utilize this compound as a key building block for constructing synthetic DNA and RNA sequences.
- Protein-RNA interaction research relies on 2'-O-Methylguanosine to study molecular recognition and binding mechanisms.
- Biomedical research incorporates this compound in the development of therapeutic agents and diagnostic tools.
- Molecular biology experiments use it as a reagent for creating custom oligonucleotides and nucleic acid probes.
| Brand | TCI |
|---|---|
| CAS number | 2140-71-8 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Chemical Biology > Nucleic Acid Chemistry |
| Pack sizes | Available in various quantities as per standard laboratory requirements |
| Physical form | Solid powder |
| Storage | Store in a cool, dry place away from light and moisture |
2'-O-Methylguanosine should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical integrity. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Proper labeling of storage containers is essential for safe handling and identification. Laboratory personnel should wear appropriate personal protective equipment when handling the compound to ensure safety. The compound is non-hazardous under normal conditions but should be handled with care to avoid any potential risks associated with chemical exposure. Regular monitoring of storage conditions ensures the compound remains stable and suitable for use in experimental applications.
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