Mometasone Furoate TCI M2354

TCI M2354 Mometasone Furoate is a synthetic corticosteroid compound of the glucocorticoid class, supplied as a pharmaceutical research reagent for laboratory experimental use. The material falls under the Life Science category, specifically within the group of biochemicals and reagents intended for pharmaceutical research. In the laboratory, this compound is commonly used as a reference standard as well as a test substance in studies examining glucocorticoid receptor activity, anti-inflammatory signalling pathways, and the evaluation of cellular responses to corticosteroid exposure at the molecular and cellular level.

The characteristic that leads researchers to select mometasone furoate is its structure as a furoate ester of a corticosteroid, which confers a relatively high lipophilicity compared with the free form of the parent molecule. This property influences its solubility in organic solvents such as dimethyl sulfoxide and ethanol, making it more straightforward to prepare stock solutions for cell-based assays. As a TCI product, the material is supplied as a solid whose identity has been verified, so that experimental results are easier to reproduce between batches and between laboratories.

In the Indonesian laboratory setting, this reagent is used in academic research groups, pharmaceutical research units, and analytical laboratories that require a corticosteroid reference material for experimental work. It supports investigations into receptor-mediated activity and anti-inflammatory mechanisms, as well as method development work where a consistently identified corticosteroid solid is needed. Its handling requirements fit the ordinary practices of a laboratory already equipped for working with pharmaceutical research reagents.

• Glucocorticoid receptor activity studies: as a corticosteroid test substance it allows researchers to probe receptor binding and receptor-mediated cellular responses under controlled experimental conditions.
• Anti-inflammatory signalling pathway research: the compound serves as a stimulus for examining how corticosteroid exposure modulates inflammatory signalling cascades at the molecular level in laboratory models.
• Cell-based assay work: its solubility in dimethyl sulfoxide and ethanol permits convenient preparation of stock solutions that can be diluted into culture media for controlled dosing experiments.
• Reference standard applications: verified identity as a TCI solid makes it suitable as a rujukan material for comparison against samples in pharmaceutical research and method development activities.
• Cellular response evaluation: researchers use it to assess how cells respond to corticosteroid exposure at both the molecular and cellular level across a range of experimental designs.

Store the material in its original tightly closed container, kept in a cool, dry place and protected from light and moisture, following the storage conditions indicated on the product label. Amber glass or other chemically compatible closed containers are appropriate for prepared stock solutions, which should be clearly labelled with the compound identity, solvent, and preparation date. Handle the solid in a fume hood or a well-ventilated area, and wear a laboratory coat, gloves, and eye protection. As a pharmaceutical research reagent intended solely for experimental use, avoid inhalation of dust and direct contact with skin, and follow institutional procedures for waste disposal.

—