TCI M2360 Minodronate Monohydrate is a nitrogen-containing bisphosphonate compound supplied as a pharmaceutical research reagent for laboratory experimental use. The material belongs to the Life Science category within the biochemicals and research reagents group. Bisphosphonates are known for their high affinity toward bone mineral, and for this reason compounds in this class are widely used in the laboratory for studies of bone metabolism, osteoclast cell activity, and the molecular mechanisms that govern the balance between bone tissue formation and resorption.
The characteristic that makes minodronate attractive to researchers is its bisphosphonate structure, which carries two phosphonate groups bound to a single central carbon atom, together with a nitrogen-containing heterocyclic side chain. This geminal diphosphonate motif gives the molecule a strong capacity to bind calcium ions, while the nitrogen heterocyclic portion is associated with its mode of action on the mevalonate pathway inside the cell. The monohydrate form indicates the presence of one water molecule within the crystal lattice, which helps keep the material as a well-defined solid so that weighing remains consistent from one preparation to the next.
In Indonesia, reagents of this type are used by research groups working in pharmacy, biomedical science, and related life science disciplines, typically within university laboratories, teaching hospital research units, and institutional research centres. The material is intended strictly for experimental laboratory work rather than clinical or therapeutic use, and is normally handled by trained personnel following the standard reagent-management practices already in place at the receiving laboratory.
TCI brochures (PDF)
- Bone Metabolism Research Reagents 2026-04-21 · p. 1
- Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 40
- Reagents for Biological Research 2025-03-11 · p. 47
- Bone metabolism research: the high mineral affinity typical of bisphosphonates makes this compound a suitable model reagent for studying how molecules interact with bone tissue in experimental systems.
- Osteoclast activity studies: as a nitrogen-containing bisphosphonate, the material is relevant to investigations of osteoclast function and the cellular processes governing bone tissue resorption in culture.
- Mevalonate pathway investigation: the nitrogen heterocyclic side chain relates this compound to mechanisms acting on the mevalonate pathway, supporting mechanistic studies at the molecular level within cells.
- Calcium ion binding experiments: the two phosphonate groups attached to a single central carbon atom give strong calcium-binding capability, making the reagent useful for chelation and mineral-interaction work.
- Pharmaceutical research reference material: supplied as a defined monohydrate solid, it serves as a consistent reference compound in pharmaceutical and biochemical research protocols requiring reproducible weighing.
| Brand | TCI |
|---|---|
| CAS number | 155648-60-5 |
| Molecular formula | — |
| Purity | — |
| Category | Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents (for Experimental Use) |
| Pack sizes | available in the standard catalogue pack sizes offered for this product code |
| Physical form | solid, supplied as the monohydrate with one water molecule in the crystal lattice |
| Storage | store according to the conditions stated on the manufacturer label and accompanying documentation |
Store the container tightly closed in a cool, dry place away from direct sunlight, moisture, and sources of heat, following the conditions indicated on the manufacturer label. Keep the material in its original container or in a chemically compatible, well-sealed vessel that protects the hydrate form from unnecessary exposure to ambient humidity, since the defined solid state supports consistent weighing. Handle in a well-ventilated area or fume hood using a laboratory coat, gloves, and eye protection, and avoid generating dust during weighing and transfer. Use clean, dry spatulas to prevent contamination, close containers promptly after use, and restrict handling to trained personnel working under the laboratory's established procedures for research reagents intended for experimental use only.
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Product Categories
- Biochemicals and ReagentsPharmaceutical Research Reagents (for Experimental Use)Anti-osteoporosis Ingredients (for Research and Experimental Use)
- Cell BiologyCancer ResearchCancer Metabolism
- Cell BiologyBone Metabolism ResearchBone Resorption Inhibitors [Bone Metabolism Research]
- Pharmaceutical Development and Drug Discovery ResearchPharmaceutical Research Reagents (for Experimental Use)Anti-osteoporosis Ingredients (for Research and Experimental Use)
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