Chloromethyl Pivalate [Amino-Protecting Agent] TCI P1012

Chemical Identity

CAS No.: 18997-19-8
Formula: C6H11ClO2
Molecular weight: 150.60 g/mol
Purity: >99.0%(GC)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: chloromethyl 2,2-dimethylpropanoate
SMILES: CC(C)(C)C(=O)OCCl
InChIKey: GGRHYQCXXYLUTL-UHFFFAOYSA-N
PubChem: CID 87885

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Chloromethyl Pivalate (TCI P1012), with CAS number 18997-19-8, is a chemical compound widely used as an amino-protecting agent in organic synthesis. It plays a critical role in laboratory settings by shielding amino groups from unwanted reactions, ensuring selective chemical transformations. This compound is essential in the development of complex molecules, particularly in the synthesis of heterocyclic compounds and peptides. Its controlled reactivity and stability make it a reliable choice for researchers aiming to achieve precise chemical outcomes.

One of the key attributes of Chloromethyl Pivalate is its stability and controlled reactivity, which allow it to be used in a variety of laboratory conditions without compromising the integrity of the reaction. It exhibits good solubility in organic solvents such as ethyl acetate and acetone, facilitating easy mixing and reaction processes. These properties make it a preferred choice for chemists who require a dependable and versatile protecting agent.

In Indonesian laboratories, Chloromethyl Pivalate is commonly used in organic chemistry research, particularly in academic and research institutions. It is especially relevant for studies involving amino group protection, such as in the synthesis of complex organic molecules. Its availability and reliability make it a standard component in many chemical laboratories across Indonesia.

Organic synthesis of heterocyclic compounds where amino group protection is essential for selective reactions.
Peptide synthesis applications requiring the temporary protection of amino functionalities to prevent premature side reactions.
Development of complex organic molecules where controlled reactivity and stability are critical for successful synthesis.
Research in academic and industrial laboratories focusing on chemical modifications of amino-containing compounds.
Use in laboratory protocols involving solubility in organic solvents for efficient reaction setup and processing.

Brand	TCI
CAS number	18997-19-8
Molecular formula	—
Purity	—
Category	Chemistry > Building Blocks > Non-Heterocyclic Building Blocks
Pack sizes	Available in various quantities as per supplier specifications
Physical form	Liquid
Storage	Store in a cool, dry place away from direct sunlight

Chloromethyl Pivalate should be stored in a cool, dry place, away from direct sunlight and sources of heat. It is recommended to use airtight containers to prevent exposure to moisture and air, which may affect its stability. Due to its controlled reactivity, it should be handled with care in a well-ventilated laboratory environment. Avoid contact with incompatible substances, and ensure proper personal protective equipment is worn during handling. Regular monitoring of storage conditions is advised to maintain the compound's integrity and effectiveness in laboratory applications.

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