Promethazine Hydrochloride TCI P2029

Promethazine Hydrochloride from TCI is the hydrochloride salt of promethazine, a phenothiazine-derived compound known as a histamine H1 receptor antagonist. TCI supplies this product as a pharmaceutical research reagent for experimental use only. It is not intended for human or veterinary treatment. In the laboratory, the compound serves as a reference material in pharmaceutical analysis and as a test compound in in vitro pharmacology studies. It is also used as a model phenothiazine molecule in analytical and physicochemical chemistry research.

As a hydrochloride salt, the compound dissolves readily in water. This makes standard and test solutions straightforward to prepare for a wide range of analytical methods. Its phenothiazine core contains an aromatic system that absorbs strongly in the ultraviolet region and oxidizes easily. These properties make it an interesting model for stability, photodegradation, and electrochemical studies. Phenothiazine compounds are generally sensitive to light and air, so storage quality strongly affects how reliable the data are. A consistent supply from an established reagent manufacturer such as TCI is therefore important for analytical laboratories that depend on reproducible results.

Promethazine is widely known in Indonesian pharmaceutical practice. As a result, it is relevant to many local laboratories, including pharmaceutical quality control laboratories, university pharmacy and chemistry departments, and research institutions working on drug analysis. Researchers use it to develop and validate analytical methods, to train students in instrumental analysis, and to study how phenothiazine derivatives behave under different conditions. Having a well-characterised research-grade reagent from a recognised brand helps Indonesian laboratories produce consistent, comparable data across their projects.

• Pharmaceutical reference analysis: the compound works as a reference material for pharmaceutical analysis, and its water solubility makes accurate standard solutions easy to prepare for routine and validation work.
• In vitro pharmacology studies: as a known histamine H1 receptor antagonist, it is a useful test compound for experimental pharmacology research carried out under controlled in vitro conditions.
• UV spectrophotometric method development: the aromatic phenothiazine core absorbs strongly in the ultraviolet region, which supports the development and teaching of UV-based analytical and quantification methods.
• Stability and photodegradation studies: because phenothiazines oxidize easily and are sensitive to light, this compound is a good model for studying degradation pathways and the effect of storage conditions.
• Electrochemical research: the easily oxidized phenothiazine system makes the compound a suitable model molecule for electrochemical studies of redox behaviour in analytical and physicochemical chemistry.

• Solubility: readily soluble in water as the hydrochloride salt

Store Promethazine Hydrochloride in its original, tightly closed container, protected from light and air, because phenothiazine compounds can degrade through oxidation and photodegradation. Amber or opaque containers, kept in a cool, dry place, help preserve the reagent's quality. Reseal the container promptly after each use to limit exposure to air and moisture. Prepare solutions shortly before use where possible, and protect them from light. Handle the material in line with standard laboratory practice: wear gloves, safety glasses, and a lab coat, avoid inhaling dust, and work in a well-ventilated area. Always consult the supplier's Safety Data Sheet before use. This product is for research and experimental use only and is not intended for human or veterinary treatment.

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