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TCI

CAS 137281-23-3

Pemetrexed TCI P2288

Pemetrexed TCI P2288

Chemical Identity

CAS No.
137281-23-3
PubChem
CID 135410875·SID 253661102
Formula
C20H21N5O6
Molecular weight
427.4 g/mol
Purity
>98.0%(HPLC)(T)
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
SMILES
C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O
InChIKey
WBXPDJSOTKVWSJ-ZDUSSCGKSA-N
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Pemetrexed is a chemical compound widely used in pharmacological and biochemical research to study drug mechanisms and the development of medical therapies. It plays a crucial role in experimental settings where the inhibition of dihydrofolate reductase enzymes is essential, particularly in cancer-related studies. As a pharmaceutical research reagent, it is vital for assessing biological activity and toxicity in laboratory experiments. Its application spans across various scientific investigations aimed at understanding how drugs interact with biological systems and how they can be optimized for therapeutic use.

One of the key reasons Pemetrexed is preferred in laboratory settings is its chemical stability under specific conditions, which allows it to be used in multiple analytical methods. Its complex molecular structure enables specific interactions with biological targets, making it ideal for high-precision research. This compound is also available in various packaging options, facilitating its use in experiments of different scales. Its versatility and reliability make it a valuable tool for researchers working in both academic and industrial environments.

In Indonesian laboratories, Pemetrexed is commonly used in applied medical and pharmacological research. It supports efforts to develop new therapies, understand biological responses to drugs, and test the efficacy and safety of pharmacological compounds. Its availability ensures that researchers can conduct experiments with consistent and reliable results, contributing to advancements in medical science and drug development.

  • Cancer research involving enzyme inhibition and drug mechanism studies benefits from Pemetrexed’s ability to target dihydrofolate reductase, making it ideal for studying anti-cancer therapies.
  • Pharmacological toxicity testing relies on Pemetrexed to evaluate the safety and biological impact of drug candidates in controlled environments.
  • Biochemical assays require Pemetrexed for its stability and reactivity, supporting accurate measurement of enzyme activity and drug interactions.
  • Drug development projects use Pemetrexed to assess the effectiveness of potential therapeutic agents in pre-clinical trials.
  • Medical research applications leverage Pemetrexed’s specificity to investigate biological responses and optimize treatment strategies for various diseases.

Brand TCI
CAS number 137281-23-3
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents
Pack sizes Available in multiple packaging options for different experimental scales
Physical form —
Storage Store in a cool, dry place away from direct sunlight

Pemetrexed should be stored in a cool, dry environment, away from direct sunlight and sources of heat. It is recommended to keep the compound in airtight containers to prevent moisture absorption and contamination. Proper labeling of storage containers is essential to ensure safe handling and prevent accidental exposure. In laboratory settings, it is important to follow standard safety protocols, including the use of personal protective equipment when handling the compound. Regular monitoring of storage conditions helps maintain the integrity and stability of the reagent, ensuring its effectiveness in research applications. Always follow established guidelines for chemical storage to minimize risks and ensure compliance with laboratory safety standards.

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