RuCl[(R,R)-Tsdpen](mesitylene) TCI R0127

Chemical Identity

CAS No.: 174813-82-2
PubChem: CID 91972075·SID 253659918
Formula: C30H33ClN2O2RuS
Molecular weight: 622.2 g/mol
Purity: >90%(HPLC)
Reference databases: ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: [(1R,2R)-2-amino-1,2-diphenylethyl]-(4-methylphenyl)sulfonylazanide;ruthenium(2+);1,3,5-trimethylbenzene;chloride
SMILES: CC1=CC=C(C=C1)S(=O)(=O)[N-][C@H](C2=CC=CC=C2)[C@@H](C3=CC=CC=C3)N.CC1=CC(=CC(=C1)C)C.[Cl-].[Ru+2]
InChIKey: XBNBOGZUDCYNOJ-AGEKDOICSA-M

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RuCl[(R,R)-Tsdpen](mesitylene) is a chiral catalyst used in asymmetric synthesis, playing a crucial role in catalytic reactions that require enantioselectivity. This compound is part of a broader class of chiral reagents designed to facilitate the formation of specific stereoisomers, making it indispensable in modern synthetic chemistry. Its application extends to the development of pharmaceutical compounds, where precise control over stereochemistry is essential for achieving desired biological activity. In laboratory settings, this material is valued for its ability to enhance reaction efficiency while maintaining the integrity of the substrate.

One of the key properties that make RuCl[(R,R)-Tsdpen](mesitylene) a preferred choice is its high chiral stability. This stability ensures consistent performance across multiple reaction cycles, reducing variability in experimental outcomes. Additionally, its ability to selectively accelerate reactions without altering the fundamental structure of the substrate makes it ideal for complex synthetic pathways. The compound's effectiveness in promoting asymmetric induction is further enhanced by its compatibility with a wide range of reaction conditions, allowing researchers to tailor experimental parameters for optimal results.

In Indonesian laboratories, RuCl[(R,R)-Tsdpen](mesitylene) is commonly used in organic chemistry research, particularly in pharmaceutical and complex molecule synthesis. It supports the development of new compounds with therapeutic potential, contributing to advancements in drug discovery and chemical innovation. Its reliability and performance make it a trusted tool for researchers aiming to achieve high selectivity and yield in their synthetic processes.

TCI brochures (PDF)

Ruthenium Complex Catalysts for Asymmetric Transfer Hydrogenation of Ketons 2026-01-30 · p. 2
Hydrogenation Catalysts 2025-11-10 · p. 7

Related TCI products

Asymmetric Synthesis: This compound is ideal for creating chiral molecules with high enantioselectivity, essential for pharmaceutical development.
Pharmaceutical Research: It supports the synthesis of bioactive compounds, enabling the production of drugs with specific stereochemistry.
Organic Chemistry Studies: Its use in complex molecule synthesis allows for the exploration of new chemical structures and reaction mechanisms.
Catalytic Reaction Optimization: It enhances reaction efficiency while maintaining substrate integrity, making it suitable for controlled synthetic pathways.
Drug Discovery Programs: Its ability to produce stereospecific products is vital in the development of new therapeutic agents.

Brand	TCI
CAS number	174813-82-2
Molecular formula	—
Purity	—
Category	Chemistry > Asymmetric Synthesis > Chiral Catalysts, Chiral Ligands, Chiral Reagents
Pack sizes	Available in various quantities as per supplier specifications
Physical form	Solid or liquid, depending on formulation
Storage	Store in a cool, dry place away from light and moisture

This compound should be stored in a cool, dry environment, away from direct sunlight and sources of heat. It is recommended to use airtight containers to prevent exposure to moisture and air, which may affect its stability. Proper labeling of storage containers is essential to ensure safe handling and prevent cross-contamination. Laboratory personnel should wear appropriate personal protective equipment, such as gloves and safety goggles, when handling this material. Due to its chiral nature, it is important to maintain consistent storage conditions to preserve its catalytic activity and selectivity. Always follow standard laboratory safety protocols to ensure safe and effective use.

References cited in the TCI brochure

Akio Fujii. Ruthenium(II)-Catalyzed Asymmetric Transfer Hydrogenation of Ketones Using a Formic Acid−Triethylamine Mixture Journal of the American Chemical Society, 1996. doi:10.1021/ja954126l
Issaku Yamada. Asymmetric Transfer Hydrogenation of Benzaldehydes Organic Letters, 2000. doi:10.1021/ol0002119