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TCI

CAS 192139-90-5

RuCl[(S,S)-Tsdpen](p-cymene) TCI R0124

RuCl[(S,S)-Tsdpen](p-cymene) TCI R0124

Chemical Identity

CAS No.
192139-90-5
PubChem
CID 11549108·SID 253659917
Formula
C31H35ClN2O2RuS
Molecular weight
636.2 g/mol
Purity
>90%(HPLC)
Reference databases
ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
[(1S,2S)-2-amino-1,2-diphenylethyl]-(4-methylphenyl)sulfonylazanide;1-methyl-4-propan-2-ylbenzene;ruthenium(2+);chloride
SMILES
CC1=CC=C(C=C1)C(C)C.CC1=CC=C(C=C1)S(=O)(=O)[N-][C@@H](C2=CC=CC=C2)[C@H](C3=CC=CC=C3)N.[Cl-].[Ru+2]
InChIKey
AZFNGPAYDKGCRB-XCPIVNJJSA-M
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TCI R0124 192139-90-5 RuCl[(S,S)-Tsdpen](p-cymene) is a chiral catalyst used in asymmetric synthesis to facilitate stereoselective reactions. This compound plays a crucial role in organic chemistry laboratories where precise control over the stereochemistry of products is essential. Its unique structure allows it to act as a highly efficient chiral catalyst, guiding chemical reactions toward the desired enantiomer with high specificity. This makes it an indispensable tool for researchers aiming to produce optically active compounds with controlled stereochemistry.

The compound is known for its high reactivity and stability, which contribute to its effectiveness in catalytic processes. Its chiral nature enables it to selectively interact with substrates, promoting the formation of specific stereoisomers. This selectivity is vital in applications such as pharmaceutical development, where the stereochemistry of a compound can significantly affect its biological activity. Its ability to maintain activity without significant degradation further enhances its reliability in laboratory settings.

In Indonesian laboratories, this compound is widely used in organic chemistry research, particularly in asymmetric synthesis and the development of new compounds. It is a preferred choice for institutions and research centers that require precise control over stereochemical outcomes. Its application extends to the pharmaceutical and chemical industries, where it supports the creation of bioactive compounds and advanced chemical products.

  • Asymmetric Synthesis: This compound is ideal for asymmetric synthesis due to its chiral structure, which enables precise control over the stereochemistry of reaction products.
  • Pharmaceutical Research: It is used in drug development to produce optically active compounds with specific stereochemical configurations.
  • Organic Chemistry Studies: It supports research in organic chemistry by facilitating stereoselective reactions in laboratory settings.
  • Catalytic Processes: Its high reactivity and stability make it suitable for catalytic applications requiring efficient and selective reactions.
  • Bioactive Compound Development: It is employed in the synthesis of bioactive compounds, where stereochemistry plays a critical role in biological activity.

Brand TCI
CAS number 192139-90-5
Molecular formula —
Purity —
Category Chemistry > Asymmetric Synthesis > Chiral Catalysts, Chiral Ligands, Chiral Reagents
Pack sizes Available in various quantities as per supplier specifications
Physical form Solid or powder, depending on the packaging
Storage Store in a cool, dry place away from moisture and direct sunlight

This compound should be stored in a cool, dry environment to maintain its stability and effectiveness. It is recommended to keep it in a sealed container to prevent exposure to moisture and air, which could affect its performance. Due to its chemical nature, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Avoid direct contact with skin or inhalation of vapors. It is important to store it in a well-ventilated area and ensure that it is not exposed to extreme temperatures. Regular inspection of storage conditions is advised to maintain the integrity of the compound throughout its shelf life.

References cited in the TCI brochure

  1. Akio Fujii. Ruthenium(II)-Catalyzed Asymmetric Transfer Hydrogenation of Ketones Using a Formic Acid−Triethylamine Mixture Journal of the American Chemical Society, 1996. doi:10.1021/ja954126l
  2. Kazuhiko Matsumura. Asymmetric Transfer Hydrogenation of α, β-Acetylenic Ketones Journal of the American Chemical Society, 1997. doi:10.1021/ja971570a
  3. Nobuyuki Uematsu. Asymmetric Transfer Hydrogenation of Imines Journal of the American Chemical Society, 1996. doi:10.1021/ja960364k