RuCl[(R,R)-Tsdpen](p-cymene) TCI R0125

Chemical Identity

CAS No.: 192139-92-7
PubChem: CID 46846568·SID 253659916
Formula: C31H35ClN2O2RuS
Molecular weight: 636.2 g/mol
Purity: >90%(HPLC)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: [(1R,2R)-2-amino-1,2-diphenylethyl]-(4-methylphenyl)sulfonylazanide;1-methyl-4-propan-2-ylbenzene;ruthenium(2+);chloride
SMILES: CC1=CC=C(C=C1)C(C)C.CC1=CC=C(C=C1)S(=O)(=O)[N-][C@H](C2=CC=CC=C2)[C@@H](C3=CC=CC=C3)N.[Cl-].[Ru+2]
InChIKey: AZFNGPAYDKGCRB-AGEKDOICSA-M

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Berat 200mg 1g

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TCI R0125 192139-92-7 RuCl[(R,R)-Tsdpen](p-cymene) is a specialized chiral catalyst used in asymmetric synthesis to facilitate chemical reactions with high selectivity. This compound plays a crucial role in laboratories by enabling the production of molecules with specific stereochemical configurations, which is essential for creating compounds with defined biological activity. Its unique structure allows it to act as a chiral directing agent, guiding reactions toward desired products with minimal by-products. This makes it an essential tool in modern synthetic chemistry, particularly in applications requiring precise control over molecular architecture.

The compound’s chiral nature and complex structure, comprising a rutenium complex with the chiral ligand (R,R)-Tsdpen and p-cymene, make it a preferred choice for asymmetric catalysis. Its ability to influence reaction pathways and enhance enantioselectivity is unmatched in many synthetic processes. This characteristic is particularly valuable in the development of pharmaceuticals and fine chemicals, where the stereochemistry of a molecule can significantly impact its biological activity and therapeutic potential. Its effectiveness in achieving high enantiomeric excess is a key factor in its widespread use.

In Indonesian laboratories, this compound is commonly used by researchers and academic institutions for advanced chemical synthesis and innovation. Its application is particularly relevant in pharmaceutical research, organic chemistry, and material science. The compound’s reliability and performance in controlled environments make it a go-to reagent for high-precision chemical processes, supporting both academic and industrial research efforts.

TCI brochures (PDF)

Ruthenium Complex Catalysts for Asymmetric Transfer Hydrogenation of Ketons 2026-01-30 · p. 2
Hydrogenation Catalysts 2025-11-10 · p. 7

Related TCI products

Asymmetric synthesis for producing pharmaceutical compounds with specific stereochemistry, as the compound's chiral nature allows precise control over enantiomeric outcomes.
Organic chemistry research for developing novel compounds with defined molecular configurations, leveraging its catalytic efficiency in complex reaction systems.
Material science applications in creating advanced materials with tailored properties, due to its ability to influence reaction pathways and product structures.
Drug discovery projects requiring high enantioselectivity, as the compound enables the synthesis of active pharmaceutical ingredients with desired stereochemistry.
Academic research in chemical synthesis, where its reliability and performance support the development of new synthetic methodologies and chemical innovations.

Brand	TCI
CAS number	192139-92-7
Molecular formula	—
Purity	—
Category	Chemistry > Asymmetric Synthesis > Chiral Catalysts, Chiral Ligands, Chiral Reagents
Pack sizes	Available in various quantities as per standard laboratory supply
Physical form	Solid or liquid, depending on the specific formulation
Storage	Store in a cool, dry place away from light and moisture

This compound should be stored in a cool, dry environment, away from direct sunlight and sources of heat. It is recommended to use airtight containers made of glass or high-density polyethylene to prevent contamination and maintain stability. Due to its chiral nature and chemical complexity, it is important to handle it with care, using appropriate personal protective equipment such as gloves and safety goggles. Ensure that the storage area is well-ventilated to minimize exposure to vapors. Avoid contact with incompatible substances and follow standard laboratory safety protocols to ensure safe handling and use.

References cited in the TCI brochure

Akio Fujii. Ruthenium(II)-Catalyzed Asymmetric Transfer Hydrogenation of Ketones Using a Formic Acid−Triethylamine Mixture Journal of the American Chemical Society, 1996. doi:10.1021/ja954126l
Kazuhiko Matsumura. Asymmetric Transfer Hydrogenation of α, β-Acetylenic Ketones Journal of the American Chemical Society, 1997. doi:10.1021/ja971570a
Nobuyuki Uematsu. Asymmetric Transfer Hydrogenation of Imines Journal of the American Chemical Society, 1996. doi:10.1021/ja960364k