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TCI

CAS 147098-20-2

Rosuvastatin Calcium TCI R0180

Rosuvastatin Calcium TCI R0180

Chemical Identity

CAS No.
147098-20-2
PubChem
CID 5282455·SID 253661249
Formula
C44H54CaF2N6O12S2
Molecular weight
1001.1 g/mol
Purity
>95.0%(HPLC)(N)
Reference databases
ChEBI·ChemSpider·ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
calcium bis((E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate)
SMILES
CC(C1=NC(=NC(=C1/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-])C2=CC=C(C=C2)F)N(S(=O)(=O)C)C)C.CC(C1=NC(=NC(=C1/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-])C2=CC=C(C=C2)F)N(S(=O)(=O)C)C)C.[Ca+2]
InChIKey
LALFOYNTGMUKGG-BGRFNVSISA-L
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Rosuvastatin Calcium TCI R0180, with CAS number 147098-20-2, is a chemical compound widely used in life science laboratory experiments. As a calcium salt of rosuvastatin, it functions as an HMG-CoA reductase inhibitor, making it essential for research into cholesterol metabolism and cardiovascular diseases. This compound is commonly utilized in biochemical and pharmacological studies to evaluate the effects of statins on lipid profiles and related metabolic pathways. Its role extends to enzyme inhibition studies, where it helps in understanding the mechanisms of lipid-lowering drugs and their therapeutic applications.

The chemical properties of Rosuvastatin Calcium make it a preferred choice for high-precision scientific applications. It exhibits excellent solubility in organic solvents, which facilitates its use in various chemical reactions and synthesis processes. The compound maintains high purity and chemical stability, ensuring reliable results in analytical and experimental procedures. These characteristics make it suitable for use in both basic and applied research settings, where accuracy and consistency are critical. Its consistent performance and purity level also support reproducibility in laboratory experiments, enhancing the credibility of scientific findings.

In Indonesian laboratories, Rosuvastatin Calcium is frequently used in research related to public health and metabolic disorders. It plays a key role in studies examining the impact of hypolipidemic drugs on lipid metabolism and in the development of new therapeutic agents. Its relevance extends to pharmacological research, where it helps in evaluating drug efficacy and safety. Due to its reliability and versatility, it is a valuable resource for researchers working on cardiovascular and metabolic disease models.

  • Pharmacological research utilizes Rosuvastatin Calcium to study the mechanism of action of statins in lowering cholesterol levels and preventing cardiovascular diseases.
  • Biochemical analysis employs this compound to assess enzyme inhibition and metabolic pathways related to lipid metabolism in cellular and tissue samples.
  • Drug development projects use Rosuvastatin Calcium as a model compound to evaluate the efficacy and safety of new hypolipidemic agents in preclinical trials.
  • Enzyme inhibition studies benefit from its role as a specific inhibitor of HMG-CoA reductase, aiding in the investigation of metabolic enzyme functions.
  • Metabolic disorder research incorporates this compound to explore the impact of lipid-lowering drugs on metabolic profiles and disease progression in experimental models.

Brand TCI
CAS number 147098-20-2
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Enzymes, Enzyme Inhibitors, Enzyme Substrates
Pack sizes Available in various quantities as per standard laboratory supply formats
Physical form Solid powder
Storage Store in a cool, dry place away from moisture and direct sunlight

Rosuvastatin Calcium should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is recommended to keep the compound in a tightly sealed container to minimize exposure to moisture and air. Due to its potential reactivity with certain substances, it should be handled in a well-ventilated area, preferably under a fume hood. Avoid contact with incompatible materials such as strong acids or bases. When working with this compound, it is essential to follow standard laboratory safety protocols, including the use of personal protective equipment. Proper storage and handling ensure the integrity of the compound and the safety of laboratory personnel.

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