Resazurin Sodium Salt TCI R0203

TCI R0203 Resazurin Sodium Salt (CAS 62758-13-8) is the sodium salt of resazurin, a phenoxazine dye widely known as a redox indicator and as an indicator of cellular metabolic activity. In its oxidized form, resazurin is blue and almost non-fluorescent. When metabolically active living cells reduce it, the compound becomes resorufin, which is pink and strongly fluorescent. This change makes resazurin an important tool in cell biology, microbiology and food quality testing laboratories, where it offers a simple way to measure cell viability and microbial activity.

Laboratories choose resazurin because it gives two signals at once. The color change can be seen by eye or read on a spectrophotometer, and the change in fluorescence can be measured on a microplate reader. Resazurin-based assays are usually simple: researchers add the solution to culture wells and incubate, which suits testing many samples at the same time. Because the dye is relatively gentle on cells over short incubation times, cells can be monitored without being lysed. The sodium salt form dissolves easily in water or buffer solutions, so working solutions are straightforward to prepare.

In Indonesian laboratories, resazurin sodium salt is commonly used in university research groups, pharmaceutical and biotechnology research facilities, and food and dairy testing laboratories. Researchers use it to assess cell viability in culture, to screen how compounds affect cell growth, and to monitor microbial activity in samples. Its simple workflow and compatibility with standard plate readers make it practical both for routine quality checks and for academic research projects that need reliable, repeatable viability data.

• Cell viability assays: metabolically active cells reduce blue resazurin to pink, fluorescent resorufin, which gives a direct and measurable readout of how many cells in a culture are alive.
• Cytotoxicity and compound screening: the simple add-and-incubate format works well in multiwell plates, so researchers can test many compounds or concentrations against cell cultures in parallel.
• Microbial activity testing: microorganisms reduce resazurin as they grow, so microbiology laboratories use the color and fluorescence change to show whether microbes are present and active in a sample.
• Food and dairy quality testing: the visible color change offers a simple way to estimate microbial activity in food samples, which supports routine quality control in food testing laboratories.
• Redox indicator studies: as a well-known phenoxazine redox indicator, resazurin shows the reduction state of a system through a clear blue-to-pink transition that can be observed or measured.

Store Resazurin Sodium Salt in its original, tightly closed TCI container under the conditions stated on the product label and Safety Data Sheet. Keep it in a cool, dry place away from direct light, moisture and incompatible materials, because dyes and redox indicators can degrade when exposed to light or air. Prepared solutions should go in clean, clearly labeled containers, preferably amber or light-protected, and should be prepared fresh or stored as recommended in the relevant assay protocol. Handle the material in line with good laboratory practice. Wear gloves, safety glasses and a lab coat, avoid creating dust, and avoid contact with skin and eyes. Read the Safety Data Sheet before use, and dispose of waste according to local regulations and institutional procedures. This product is intended for research and experimental use only.

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