Sodium Cholate from Bovine Bile [for Biochemical Research] TCI S0596

Chemical Identity

CAS No.: 361-09-1
PubChem: CID 44629917·SID 87560414
Formula: C24H39NaO5
Molecular weight: 430.6 g/mol
Purity: >98.0%(T)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: sodium 4-[(3R,7R,10S,12S,13R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
SMILES: CC(CCC(=O)[O-])C1CCC2[C@@]1([C@H](CC3C2[C@@H](CC4[C@@]3(CC[C@H](C4)O)C)O)O)C.[Na+]
InChIKey: NRHMKIHPTBHXPF-SDTWYKGJSA-M

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Sodium Cholate is a widely used chemical compound in biochemical research, serving as a non-ionic surfactant with essential functions in laboratory settings. It is derived from bovine bile and is known for its ability to emulsify and disrupt lipids, making it a valuable tool in various experimental procedures. This compound is commonly employed to facilitate protein precipitation, cell membrane disruption, and lipid extraction, playing a critical role in the analysis of biological compositions and membrane structures. Its amphipathic nature allows it to interact effectively with both lipid and protein molecules, enhancing its utility in diverse biochemical applications.

One of the key reasons Sodium Cholate is preferred in laboratories is its amphipathic properties, which enable it to interact with a wide range of biomolecules. This characteristic makes it highly effective in applications such as lipoprotein breakdown and protein precipitation. Additionally, its non-ionic nature ensures stability in various experimental conditions, making it a reliable reagent for consistent results. Sodium Cholate’s ability to modify cell membranes and aid in lipid component analysis further solidifies its position as a preferred choice in biochemical research.

In Indonesian laboratories, Sodium Cholate is a crucial component in biomedical, pharmacological, and biotechnological research. It is frequently used to clarify molecular structures and understand biological mechanisms, supporting both academic and industrial research efforts. Its availability through suppliers like AMI Scientific ensures that researchers in Indonesia have access to this essential reagent for their experiments.

TCI brochures (PDF)

Protein and Biological Sample Preparation Reagents 2026-09-10 · p. 4
Steroids 2026-07-28 · p. 6
Reagents for Biological Research 2025-03-11 · p. 23

Related TCI products

Protein precipitation is enhanced by Sodium Cholate due to its ability to disrupt lipid membranes and facilitate the aggregation of proteins, making it ideal for purification and analysis.
Cell membrane disruption is effectively achieved using Sodium Cholate, as it can solubilize membrane lipids, aiding in the study of membrane composition and function.
Lipid extraction processes benefit from Sodium Cholate’s emulsifying properties, allowing for the efficient separation and analysis of lipid components in biological samples.
Membrane modification studies utilize Sodium Cholate to alter membrane structures, enabling researchers to investigate the effects of lipid composition on cellular behavior.
Biochemical analysis of biological samples is supported by Sodium Cholate, as it aids in the clarification of molecular structures and the study of biological mechanisms.

Brand	TCI
CAS number	361-09-1
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Detergents (for Biochemistry)
Pack sizes	Available in various sizes as per supplier specifications
Physical form	Powder or crystalline solid
Storage	Store in a cool, dry place away from moisture and light

Sodium Cholate should be stored in a cool, dry place, away from moisture and direct light to maintain its chemical integrity. It is recommended to use airtight containers to prevent exposure to humidity, which could affect its performance. As a chemical reagent, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Proper ventilation is also essential when working with this compound to minimize inhalation risks. Regular monitoring of storage conditions will help ensure the reagent remains effective for its intended applications.

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