Tetraethylammonium Fluoride Hydrate TCI T0838

Chemical Identity

CAS No.: 98330-04-2
PubChem: CID 69582·SID 87576674
Formula: C8H20FN
Molecular weight: 149.25 g/mol
Purity: >95.0%(T)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: tetraethylazanium fluoride
SMILES: CC[N+](CC)(CC)CC.[F-]
InChIKey: QSUJAUYJBJRLKV-UHFFFAOYSA-M

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Tetraethylammonium Fluoride Hydrate (TEAFH) is a chemical compound widely used in synthetic laboratory applications. It serves as a versatile reagent in organic chemistry, particularly in processes involving protection, deprotection, and derivatization. TEAFH is commonly employed as a source of highly reactive fluoride ions, which are essential for catalyzing complex chemical transformations. Its utility spans across various synthetic pathways, making it a fundamental component in the toolkit of organic chemists. The compound's reactivity and selectivity allow it to interact with a wide range of functional groups, enabling the synthesis of intricate molecular structures.

TEAFH is preferred due to its high purity and stability under controlled laboratory conditions. Its solid form facilitates precise weighing and handling, which is critical in research settings requiring accuracy. The compound's ability to participate in multiple reaction types, such as nucleophilic substitutions and acid-catalyzed reactions, further enhances its appeal. Additionally, its solubility in polar solvents makes it compatible with a variety of reaction protocols. These properties make TEAFH a reliable and efficient reagent for both academic and industrial research.

In Indonesian laboratories, TEAFH is frequently used in organic chemistry research, particularly in higher education institutions and research centers. It supports the development of new compounds and applications in pharmaceutical and material sciences. Its availability in solid form and ease of use make it a favored choice among researchers. The compound's role in advancing chemical synthesis is well recognized, contributing to the growth of scientific innovation in Indonesia.

TCI brochures (PDF)

Quaternary Ammonium Salts 2025-11-10 · p. 3

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Organic synthesis reactions benefit from TEAFH's ability to provide reactive fluoride ions, enabling efficient deprotection and derivatization of complex molecules.
In pharmaceutical research, TEAFH is used to modify functional groups, aiding in the development of new drug compounds with desired properties.
Material science applications utilize TEAFH for the synthesis of advanced polymers and functional materials through controlled chemical modifications.
Analytical chemistry laboratories use TEAFH as a reagent in derivatization processes to enhance the detectability of compounds in chromatographic analysis.
Academic research in Indonesia relies on TEAFH for teaching and experimental purposes, supporting both undergraduate and graduate-level studies in chemistry.

Brand	TCI
CAS number	98330-04-2
Molecular formula	—
Purity	—
Category	Chemistry > Synthetic Reagents > Protection, Deprotection, Derivatization
Pack sizes	Available in various quantities as per standard laboratory supply
Physical form	Solid
Storage	Store in a cool, dry place away from moisture and direct sunlight

TEAFH should be stored in a cool, dry environment to maintain its stability and prevent degradation. It is recommended to keep the compound in a sealed container to minimize exposure to moisture, which can affect its reactivity. Due to its hygroscopic nature, it should be handled in a controlled laboratory setting with appropriate ventilation. Avoid contact with incompatible materials such as strong oxidizing agents. Always use proper personal protective equipment when handling TEAFH to ensure safety. Regular monitoring of storage conditions is advised to maintain the compound's integrity and effectiveness in chemical applications.

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