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TCI

CAS 4525-65-9

2,4,6-Trichlorophenyl Formate TCI T3121

2,4,6-Trichlorophenyl Formate TCI T3121

Chemical Identity

CAS No.
4525-65-9
PubChem
CID 53750963·SID 253661984
Formula
C7H3Cl3O2
Molecular weight
225.5 g/mol
Purity
>97.0%(HPLC)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2,4,6-trichlorophenyl) formate
SMILES
C1=C(C=C(C(=C1Cl)OC=O)Cl)Cl
InChIKey
YSUDXADDVAYVNS-UHFFFAOYSA-N
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2,4,6-Trichlorophenyl Formate (CAS 4525-65-9) is a high-quality chemical from TCI, supplied as HPLC Grade.

Application: Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.

Specifications:

  • Molecular formula: C7H3Cl3O2
  • CAS number: 4525-65-9
  • Purity: >97.0%(HPLC)
  • TCI product code: T3121

Synonyms: Formic Acid 2,4,6-Trichlorophenyl Ester

Available from AMI Scientific, the authorised TCI distributor in Indonesia. Contact us for pricing and stock availability — we ship throughout Indonesia.

Advantages (TCI brochure)

  • Stable crystalline solid at room temperature.
  • Rapidly decomposes by treatment with a trialkylamine; in situ generated CO is applied to carbonylation.

TCI brochures (PDF)

From the TCI brochure

  • Carbonylation of aryl or alkenyl halides (X = I, Br, OTf) with Pd(OAc)2/Xantphos and NR3
  • Synthesis of esters, thioesters and amides by reaction with nucleophiles OR2, SR2 and NR2

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References cited in the TCI brochure

  1. Tsuyoshi Ueda. Trichlorophenyl Formate: Highly Reactive and Easily Accessible Crystalline CO Surrogate for Palladium-Catalyzed Carbonylation of Aryl/Alkenyl Halides and Triflates Organic Letters, 2012. doi:10.1021/ol302593z
  2. . Pd-Catalyzed External-CO-Free Carbonylation: Preparation of 2,4,6-Trichlorophenyl 3,4-Dihydronaphthalene-2-Carboxylate Organic Syntheses, 2014. doi:10.15227/orgsyn.091.0039