Chemical Chaperones

Chemical Chaperones — includes osmolytes and small molecules such as bile acid derivatives, betaine, and trehalose that chemically help maintain the conformational stability of proteins and reduce aggregation in cell-based and in vitro experimental systems.

Chemical Chaperones are used by biochemistry and molecular biology researchers as in vitro test materials to study protein folding, endoplasmic reticulum homeostasis, and cellular stress responses in cell cultures. Compounds such as trehalose dihydrate and trimethylamine N-oxide are often added to culture media or protein reconstitution systems to observe their effects on the structural stability of macromolecules in laboratory experiments.

Product examples in this collection: TCI U0030 128-13-2 Ursodeoxycholic Acid, TCI B6796 107-43-7 Betaine Anhydrous [for Biochemical Research], TCI T4321 62637-93-8 Trimethylamine N-Oxide Dihydrate [for Biochemical Research], TCI D0798 67-68-5 Dimethyl Sulfoxide, TCI T4320 6138-23-4 D-(+)-Trehalose Dihydrate [for Biochemical Research], TCI D6676 189999-35-7 Dibenzo[b,d]iodol-5-ium Trifluoromethanesulfonate, TCI T4319 107-35-7 2-Aminoethanesulfonic Acid [for Biochemical Research], TCI I0040 87-89-8 myo-Inositol.

Pay attention to the purity grade marked for biochemical research (for Biochemical Research), the hydrate or anhydrous form, and solubility in the buffer systems used in cell experiment protocols. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under Biochemicals & Biological Reagents, often used together in a single laboratory workflow:

Back to Biochemicals & Biological Reagents. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — for availability checks and lead time directly from Japan.

Related TCI catalogs (PDF)

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