Collection: Hypervalent Iodine Compounds [Synthetic Reagents]

Hypervalent Iodine Compounds [Synthetic Reagents] — compiles hypervalent iodine compounds such as diaryliodonium salts and benziodoxole derivatives that function as arylation reagents as well as selective oxidants in organic synthesis. This reagent group serves as an alternative to transition metals for forming carbon-carbon or carbon-heteroatom bonds and for oxidizing certain functional groups.

Hypervalent Iodine Compounds are used by synthetic organic chemists for electrophilic arylation reactions using diaryliodonium salts, transferring aryl groups to nucleophiles in forming carbon-carbon and carbon-heteroatom bonds without precious metal catalysts. Reagents such as 2-iodoxybenzoic acid and benziodoxole derivatives are used as mild oxidants to convert alcohols into aldehydes or ketones, making this group a popular choice in multistep syntheses that are sensitive to harsh reaction conditions.

Example products in this collection: TCI I0791 61717-82-6 2-Iodoxybenzoic Acid (stabilized with Benzoic Acid + Isophthalic Acid), TCI B5573 1868173-47-0 4-Biphenylyl(2,4,6-trimethoxyphenyl)iodonium Trifluoromethanesulfonate, TCI T3967 55962-05-5 4-Methyl-N-(phenyl-lambda3-iodaneylidene)benzenesulfonamide, TCI B5598 60565-88-0 Bis(4-methylphenyl)iodonium Hexafluorophosphate, TCI T3622 1868173-15-2 [(4-Trifluoromethyl)phenyl](2,4,6-trimethoxyphenyl)iodonium p-Toluenesulfonate, TCI B6071 194999-85-4 Bis(4-tert-butylphenyl)iodonium Nonafluoro-1-butanesulfonate, TCI T3590 181934-34-9 1-[2-(Triisopropylsilyl)ethynyl]-3,3-bis(trifluoromethyl)-1,2-benziodoxole, TCI B6355 5421-53-4 Bis(4-tert-butylphenyl)iodonium Chloride.

Selecting hypervalent iodine reagents requires attention to the counter-anion (such as triflate, tosylate, or hexafluorophosphate), which affects reactivity and solubility, as well as the storage stability of materials stabilized with carboxylic acids. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under Organic Synthesis Reagents, often used together in one laboratory workflow:

• C-C Bond Formation [Synthetic Reagents]
• C-X(Non-Halogen) Bond Formation [Synthetic Reagents]
• Protection, Deprotection, Derivatization
• Acids, Bases [Synthetic Reagents]
• Chelation/Complexation Compounds
• Phase Transfer Catalysts

This collection is further divided into 2 more specific groups:

• Arylation [Synthetic Reagents]
• Hypervalent Iodine [Oxidation]

Back to Organic Synthesis Reagents. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official TCI Japan distributor in Indonesia — for stock availability checks and lead time directly from Japan.