Collection: Amphoteric Surfactants (for Biochemistry)

Amphoteric Surfactants (for Biochemistry) — includes zwitterionic surfactants derived from sulfobetaine with varying alkyl chains that function to dissolve and stabilize membrane proteins without disrupting their native structure, making them mild detergents for biochemistry and structural biology applications.

Amphoteric surfactants such as dodecyldimethyl(3-sulfopropyl)ammonium hydroxide are used by protein biochemistry researchers for the extraction and solubilization of membrane proteins prior to electrophoresis or crystallography, because they do not drastically denature proteins. The choice of alkyl chain length (C8 to C16) is adjusted to the solubilization strength required for each type of cell membrane.

Example products in this collection: TCI T2653 14933-09-6 Tetradecyldimethyl(3-sulfopropyl)ammonium Hydroxide Inner Salt [for Biochemical Research], TCI D3860 14933-08-5 Dodecyldimethyl(3-sulfopropyl)ammonium Hydroxide Inner Salt [for Biochemical Research], TCI H1283 2281-11-0 Hexadecyldimethyl(3-sulfopropyl)ammonium Hydroxide Inner Salt [for Biochemical Research], TCI D4246 15163-36-7 Decyldimethyl(3-sulfopropyl)ammonium Hydroxide Inner Salt [for Biochemical Research], TCI D4247 15178-76-4 Dimethyl(n-octyl)(3-sulfopropyl)ammonium Hydroxide Inner Salt [for Biochemical Research].

Adjust the alkyl chain length to the solubilization strength required, and ensure high purity because residual impurities can affect the activity of membrane proteins extracted during the solubilization process. All products are genuine products of Tokyo Chemical Industry (TCI) Japan, with purity, packaging, and storage conditions listed on the page of each item.

Other parallel categories under Detergents [Denaturation], often used together in a single laboratory workflow:

• Cationic Surfactants (for Biochemistry)
• Chaotropic Agents

Back to Detergents [Denaturation]. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — the official TCI Japan distributor in Indonesia — to check availability and lead time directly from Japan.