Collection: C-Protected Amino Acids

C-Protected Amino Acids — a collection of amino acids whose carboxyl groups are protected in the form of esters—such as methyl, ethyl, or benzyl esters—while the amino group may remain free or also be protected with Boc or acetyl groups. This protected form maintains reaction selectivity in stepwise peptide synthesis.

C-Protected Amino Acids are used by peptide synthesis chemists to control the reactivity of carboxyl groups during amide bond formation, so that coupling can be focused on the amino group or other intended positions. Derivatives such as N-succinimidyl esters and benzyl esters in this category are also used in solution-phase and solid-phase synthesis strategies for peptide fragments and bioactive derivatives.

Example products in this collection: TCI A0118 36546-50-6 N-Acetyl-L-tyrosine Ethyl Ester Monohydrate, TCI B5537 96099-84-2 N-(tert-Butoxycarbonyl)-D-threonine Methyl Ester, TCI A0094 1906-82-7 N-Acetylglycine Ethyl Ester, TCI B5684 51513-80-5 6-[(tert-Butoxycarbonyl)amino]hexanoic Acid N-Succinimidyl Ester, TCI V0207 16652-76-9 H-Val-OBzlTos-OH, TCI B6053 58816-69-6 SB 297006, TCI V0196 21760-98-5 L-Valine Benzyl Ester, TCI B6504 15231-41-1 tert-Butyl 3-Aminopropanoate.

Pay attention to the type of protecting ester (methyl, ethyl, benzyl) and its compatibility with the amine protecting group, the stereochemical configuration (L/D), and the enantiomeric purity required for peptide synthesis. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other sibling categories under Amino Acids, often used together in one laboratory workflow:

• Biologically-modified Amino Acids
• Amino Acid Amides

Back to Amino Acids. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — for availability checks and lead times directly from Japan.