Cross-Linkers [Reagents for ADC Preparation Research]

Cross-Linkers [Reagents for ADC Preparation Research] — includes heterobifunctional cross-linker reagents, generally based on NHS esters and maleimide groups, which link two biomolecules through amine and thiol groups. This class is a core chemical component in conjugating antibodies with other molecules.

These reagents are used in antibody-drug conjugate (ADC) preparation research to link antibodies with payloads or linkers through selective reactions with lysine and cysteine. Bioconjugation researchers and biopharmaceutical developers use them to optimize the antibody-payload ratio and the stability of the resulting conjugates.

Example products in this collection: TCI U0123 185332-92-7 Sulfo-GMBS, TCI B6295 32602-11-2 2,3-Bis(bromomethyl)quinoxaline-6-carboxylic Acid, TCI S0853 64987-85-5 N-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate, TCI F1371 329223-23-6 (9H-Fluoren-9-yl)methyl [2-(Phosphonooxy)ethyl]carbamate, TCI S0819 68181-17-9 N-Succinimidyl 3-(2-Pyridyldithio)propionate, TCI F1405 77667-26-6 4-Formyl-2-nitrophenyl 2,3,4,6-Tetra-O-acetyl-beta-D-galactopyranoside, TCI S0428 55750-63-5 N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent], TCI M3763 229977-57-5 MAC Glucuronide Linker-2.

Pay attention to spacer chain length, type of reactive group (NHS ester, maleimide, pyridyl disulfide), and water solubility (for example sulfo- variants) according to the requirements of the conjugation protocol. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under Antibody-Drug Conjugates (ADC) Preparation Research Reagents, often used together in one laboratory workflow:

Back to Antibody-Drug Conjugates (ADC) Preparation Research Reagents. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — to check availability and lead time directly from Japan.

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