Collection: Silylation (Others) [GC Derivatization Reagents]

Silylation (Others) [GC Derivatization Reagents] — contains a range of silylation reagents based on the tert-butyldimethylsilyl group and its derivatives, used to convert polar compounds such as alcohols, carboxylic acids, or amines into more volatile forms. These derivatives complement the standard trimethylsilyl silylation reagents with higher stability toward hydrolysis.

Silylation (Others) [GC Derivatization Reagents] is used by laboratory analysts to derivatize samples before gas chromatography or GC-MS analysis, especially when a silyl derivative that is more resistant to hydrolysis than ordinary trimethylsilyl derivatives is required. These tert-butyldimethylsilyl-based reagents are commonly used in metabolomic, environmental, and characterization analyses of compounds with multiple polar functional groups.

Example products in this collection: TCI B1906 82112-21-8 N,O-Bis(tert-butyldimethylsilyl)acetamide [tert-Butyldimethylsilylating Agent], TCI C0605 1719-57-9 Chloro(chloromethyl)dimethylsilane, TCI B1663 94124-39-7 tert-Butylmethoxyphenylsilyl Bromide, TCI C0778 1066-35-9 Chlorodimethylsilane, TCI B1150 77377-52-7 N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide, TCI D1516 62365-34-8 1-(Dimethylethylsilyl)imidazole [Dimethylethylsilylating Agent], TCI B1043 54925-64-3 1-(tert-Butyldimethylsilyl)imidazole [tert-Butyldimethylsilylating Agent], TCI D1590 17477-29-1 Chlorodimethylpropylsilane [Dimethylpropylsilylating Agent].

Select based on the reactivity and selectivity toward the target functional group, the sensitivity to moisture that requires moisture-free handling, and the volatility of reaction by-products, which affects chromatogram cleanliness. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under GC Derivatization Reagents, often used together in one laboratory workflow:

Back to GC Derivatization Reagents. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — the official distributor of TCI Japan in Indonesia — to check availability and lead time directly from Japan.

3 products