Collection: Chiral Derivatization for Optical Purity Determination [GC Derivatization Reagents]

Chiral Derivatization for Optical Purity Determination [GC Derivatization Reagents] — contains chiral reagents such as acetoxypropionyl chloride derivatives and 1-phenylethylamine in single enantiomer form (R) and (S), which function to form diastereomeric derivatives for optical purity analysis using gas chromatography as well as HPLC.

These chiral derivatization reagents are used to convert the enantiomer pair of an analyte into diastereomers that can be separated by gas chromatography on a non-chiral column. Analytical chemists use them to determine the enantiomeric excess of products from asymmetric synthesis, especially in the development of active pharmaceutical ingredients and agrochemicals that require strict stereochemical control.

Example products in this collection: TCI A3085 53636-19-4 (R)-(+)-2-Acetoxypropionyl Chloride, TCI C1022 39637-74-6 (-)-Camphanic Chloride, TCI A1297 36394-75-9 (S)-(-)-2-Acetoxypropionyl Chloride, TCI I0334 33375-06-3 (R)-(+)-alpha-Methylbenzyl Isocyanate, TCI P0796 1445-91-6 (S)-(-)-1-Phenylethyl Alcohol, TCI I0335 14649-03-7 (S)-(-)-alpha-Methylbenzyl Isocyanate, TCI P0795 1517-69-7 (R)-(+)-1-Phenylethyl Alcohol, TCI I0336 42340-98-7 (R)-(-)-1-(1-Naphthyl)ethyl Isocyanate.

Ensure the enantiomeric purity of the reagent (high ee) and choose the (R) or (S) configuration that suits your needs so that the derivatization results do not introduce bias when determining the optical purity of the target sample. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other categories at the same level under GC Derivatization Reagents, often used together in one laboratory workflow:

• Alkylation (Esterification) [Synthetic Reagents]
• Trimethylsilylation [GC Derivatization Reagents]
• Esterification, Alkylation [GC Derivatization Reagents]
• Silylation (Others) [GC Derivatization Reagents]
• Acylation [GC Derivatization Reagents]
• GC Derivatization Reagents (Others)

Back to GC Derivatization Reagents. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — for availability and lead time checks directly from Japan.