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TCI

CAS 957-68-6

7-Aminocephalosporanic Acid TCI A1266

7-Aminocephalosporanic Acid TCI A1266

Chemical Identity

CAS No.
957-68-6
PubChem
CID 14801273·SID 87562732
Formula
C10H12N2O5S
Molecular weight
272.28 g/mol
Purity
>97.0%(HPLC)(T)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(6R)-3-(acetyloxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-4-carboxylic acid
SMILES
CC(=O)OCC1=C(S[C@@H]2C(C(=O)N2C1)N)C(=O)O
InChIKey
UUKRDQCORZUZAE-IOJJLOCKSA-N
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7-Aminocephalosporanic Acid (7-ACA) is a key chemical compound widely used in laboratory settings for the synthesis of third-generation antibiotics such as cefotaxime and ceftriaxone. As a core component in antibiotic production, it plays a vital role in the development of effective treatments against both gram-positive and gram-negative bacteria. In chemical biology and peptide chemistry, 7-ACA serves as a foundational building block for various synthetic reactions, enabling the modification of molecular structures with precision. Its presence in research laboratories underscores its importance in advancing pharmaceutical and biochemical studies.

The compound is known for its stable chemical structure, which allows it to react efficiently with a range of reagents, including acids, bases, and activating agents. This reactivity makes it an ideal candidate for chemical modifications and synthetic pathways. Additionally, 7-ACA exhibits good solubility in organic solvents, facilitating processes such as separation and isolation in laboratory procedures. These properties contribute to its versatility and reliability in both academic and industrial research environments.

In Indonesian laboratories, 7-ACA is commonly used in antibiotic research, drug development, and chemical analysis. Its availability supports local scientists in their efforts to create new medications and test the efficacy of existing antibiotics. As a critical reagent, it is essential for maintaining the quality and innovation of pharmaceutical and biochemical research in the region.

  • Antibiotic Synthesis: 7-ACA is essential for the production of third-generation cephalosporins, making it ideal for antibiotic research and development.
  • Peptide Chemistry: Its structural characteristics make it a preferred choice for modifying and synthesizing complex peptide-based compounds.
  • Drug Development: Used in the formulation of new antibiotics, it supports the creation of effective treatments for bacterial infections.
  • Chemical Analysis: Its solubility and reactivity aid in analytical procedures, enabling accurate identification and quantification in laboratory settings.
  • Research and Education: Widely used in academic institutions, it facilitates teaching and learning in chemical biology and pharmaceutical sciences.

Brand TCI
CAS number 957-68-6
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes Available in various quantities as per supplier specifications
Physical form White crystalline powder
Storage Store in a cool, dry place away from light and moisture

7-ACA should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical stability. It is recommended to use airtight containers to prevent contamination and degradation. Due to its reactivity with acids and bases, it should be handled with appropriate personal protective equipment such as gloves and safety goggles. In laboratory settings, it should be stored separately from incompatible substances to ensure safety. Proper labeling of storage containers is essential for safe handling and easy identification. Regular monitoring of storage conditions ensures the compound remains suitable for use in research applications.

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