• 2705189-79-1 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl Chloride Hydrochloride [for HPLC Labeling] - AMI Scientific
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TCI

CAS 2705189-79-1

4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl Chloride Hydrochloride [for HPLC Labeling] TCI A5579

4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl Chloride Hydrochloride [for HPLC Labeling] TCI A5579

Chemical Identity

CAS No.
2705189-79-1
PubChem
CID 44630079·SID 87563196
Formula
C22H16Cl2N2O
Molecular weight
395.3 g/mol
Purity
>97.0%(T)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
4-(4,5-diphenyl-1H-imidazol-2-yl)benzoyl chloride;hydrochloride
SMILES
C1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=C(C=C3)C(=O)Cl)C4=CC=CC=C4.Cl
InChIKey
DLCZLPBEOVPLJE-UHFFFAOYSA-N
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TCI A5579 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl Chloride Hydrochloride is a chemical compound specifically designed for use in derivatization processes within analytical chemistry. It plays a crucial role in high-performance liquid chromatography (HPLC) labeling, where it enhances the detection and identification of complex molecules in samples. This reagent is widely utilized in laboratories to improve the sensitivity and accuracy of chemical analyses, making it an essential tool for researchers working with challenging analytical tasks.

The compound is known for its stable chemical properties and good reactivity, which make it a preferred choice for derivatization reactions. Its complex molecular structure allows it to form strong bonds with target molecules, facilitating clear detection through HPLC techniques. The reagent's reliability and consistent performance ensure that it meets the high standards required in modern analytical laboratories. Its compatibility with various analytical methods further enhances its versatility in different research applications.

In Indonesian laboratories, this product is commonly used in chemical analytical research, particularly in pharmaceutical and environmental studies. It is favored for its quality and effectiveness in improving the clarity and accuracy of analytical data. Researchers and laboratories in Indonesia rely on this compound to support their work in complex chemical analyses, ensuring reliable and reproducible results. Its availability in small pack sizes makes it convenient for use in laboratory settings.

Advantages (TCI brochure)

  • Reacts with amino and hydroxy groups to form amides and esters
  • Derivatives are stable for at least 24 h at room temperature
  • Derivatives stay intact under reversed phase HPLC and separate on ODS columns
  • Detection limit 0.6-5.2 fmol per 5 µL injection (S/N = 3)

TCI brochures (PDF)

Related TCI products

  • Used in pharmaceutical research for enhancing detection of trace compounds in drug formulations through HPLC labeling.
  • Applied in environmental analysis to identify and quantify pollutants in complex environmental samples with improved sensitivity.
  • Utilized in forensic science for the analysis of organic compounds in forensic samples, improving identification accuracy.
  • Employed in food safety testing to detect contaminants and additives in food products with high specificity.
  • Applied in clinical diagnostics for the analysis of biomolecules in biological samples, supporting accurate diagnostic results.

From the TCI brochure

  • Quantitative analysis of methamphetamine and its derivatives in hair
  • Quantitative analysis of methamphetamine analogs in urine

Brand TCI
CAS number 2705189-79-1
Molecular formula —
Purity —
Category Analytical Chemistry > Analytical Reagents > Derivatization Reagents
Pack sizes Available in small quantities suitable for laboratory use
Physical form Solid
Storage —

Data from the TCI brochure

Excitation wavelength330 nm (Amide derivative, pH 9.0, acetone, r.t.)
Emission wavelength440 nm (Amide derivative, pH 9.0, acetone, r.t.)
Excitation wavelength325 nm (Chromatogram of amines, Daisopak SP-120-5-ODS-BP 4.6 mm I.D. x 250 mm)
Emission wavelength430 nm (Chromatogram of amines, Daisopak SP-120-5-ODS-BP 4.6 mm I.D. x 250 mm)
Mobile phaseCH3CN / H2O = 65 / 35; 1 mL/min (Chromatogram of phentermine and fenfluramine)

Source: TCI brochure A1096 (2026-03-10)

This reagent should be stored in a cool, dry place away from direct sunlight and moisture. It is recommended to use airtight containers to prevent exposure to air and humidity, which could affect its stability. Due to its chemical nature, it should be handled with appropriate personal protective equipment such as gloves and safety goggles. It is important to ensure that the storage area is well-ventilated to minimize any potential risks associated with handling. Proper labeling of containers is essential to ensure safe handling and prevent accidental exposure. Laboratories should follow standard safety protocols when working with this compound to maintain a safe and efficient working environment.

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Product Categories

Analytical Chemistry

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