• 140164-85-8 NBD-COCl [=4-(N-Chloroformylmethyl-N-methylamino)-7-nitro-2,1,3-benzoxadiazole] [for HPLC Labeling] - AMI Scientific
  • 140164-85-8 NBD-COCl [=4-(N-Chloroformylmethyl-N-methylamino)-7-nitro-2,1,3-benzoxadiazole] [for HPLC Labeling] - AMI Scientific
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TCI

CAS 140164-85-8

NBD-COCl [=4-(N-Chloroformylmethyl-N-methylamino)-7-nitro-2,1,3-benzoxadiazole] [for HPLC Labeling] TCI A5572

NBD-COCl [=4-(N-Chloroformylmethyl-N-methylamino)-7-nitro-2,1,3-benzoxadiazole] [for HPLC Labeling] TCI A5572

Chemical Identity

CAS No.
140164-85-8
PubChem
CID 23146122·SID 87563189
Formula
C9H7ClN4O4
Molecular weight
270.63 g/mol
Purity
>92.0%(T)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
2-[methyl-(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]acetyl chloride
SMILES
CN(CC(=O)Cl)C1=CC=C(C2=NON=C12)[N+](=O)[O-]
InChIKey
BLKGIXBLRWZLKS-UHFFFAOYSA-N
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NBD-COCl (4-(N-Chloroformylmethyl-N-methylamino)-7-nitro-2,1,3-benzoxadiazole) is a chemical compound widely used in analytical chemistry for derivatization processes. This reagent plays a crucial role in laboratory settings where high-performance liquid chromatography (HPLC) is employed for quantitative analysis. Its primary function is to act as a fluorescent label, enabling the detection and identification of target compounds with high sensitivity. By reacting with organic compounds, NBD-COCl enhances the resolution and accuracy of analytical procedures, making it an essential tool in modern chemical analysis.

The compound is favored for its strong fluorescent properties, which allow for easy detection in complex mixtures. Its chemical stability under controlled conditions ensures reliable results, while its sensitivity to moisture and light necessitates careful handling. These characteristics make NBD-COCl a preferred choice for applications requiring precision and sensitivity. The ability to produce intense fluorescence further supports its use in various analytical techniques, contributing to its popularity among researchers.

In Indonesian laboratories, NBD-COCl is extensively used in chemical analysis research, particularly in the pharmaceutical field. Its application supports the development of new drugs and the quality control of existing ones. The compound is also utilized in environmental and food safety testing, where accurate detection of trace compounds is essential. Its versatility and effectiveness make it a valuable reagent in diverse analytical contexts across Indonesia.

Related TCI products

  • HPLC Analysis: NBD-COCl is ideal for HPLC due to its fluorescent labeling properties, enabling precise detection of organic compounds in complex samples.
  • Pharmaceutical Research: It is used to label and detect drug molecules, supporting the development and quality control of pharmaceutical products.
  • Environmental Testing: The compound aids in the analysis of pollutants and contaminants in water and soil samples, providing high sensitivity and accuracy.
  • Food Safety Analysis: NBD-COCl helps in identifying and quantifying harmful substances in food samples, ensuring compliance with safety standards.
  • Biochemical Studies: It is employed in biochemical research to track and analyze biomolecules, enhancing the accuracy of analytical results.

Brand TCI
CAS number 140164-85-8
Molecular formula —
Purity —
Category Analytical Chemistry > Analytical Reagents > Derivatization Reagents
Pack sizes Available in standard laboratory quantities as per supplier specifications
Physical form Solid powder
Storage Must be stored in a dry, dark place away from light and moisture

NBD-COCl should be stored in a cool, dry environment to prevent degradation due to moisture and light exposure. It is recommended to use airtight containers made of glass or high-density polyethylene to maintain its stability. The compound is sensitive to humidity and should be kept in a desiccated cabinet or refrigerator when not in use. Laboratory personnel should wear appropriate personal protective equipment, such as gloves and safety goggles, when handling this reagent. Proper ventilation is essential to avoid inhalation of any airborne particles. Regular monitoring of storage conditions ensures the integrity and effectiveness of the reagent for analytical applications.

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Analytical Chemistry

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