Benzoyl Chloride (TCI B0105), with CAS number 98-88-4, is a versatile chemical compound widely used in organic laboratory reactions. As an aromatic halide, it serves as a key reagent in the synthesis of various aromatic compounds. Its high reactivity makes it an essential tool for chemists engaged in synthetic processes. This compound is commonly utilized in nucleophilic substitution reactions, where it acts as a reactive electrophile. Its utility spans multiple areas of organic chemistry, from the preparation of carboxylic acids to the formation of esters and heterocyclic compounds.
The reactivity of Benzoyl Chloride is primarily due to its ability to undergo nucleophilic substitution with amines, alcohols, and hydroxides. This makes it an ideal choice for reactions requiring rapid and efficient transformation of functional groups. Its strong electrophilic nature allows it to participate in a wide range of synthetic pathways. However, due to its corrosive and toxic properties, it must be handled with care. These characteristics ensure that it remains a preferred reagent in both academic and industrial research settings.
In Indonesian laboratories, Benzoyl Chloride is frequently used in organic chemistry research, particularly in the development of pharmaceutical compounds and industrial chemicals. Its high reactivity enables the synthesis of complex molecules, making it a valuable component in halogenation and substitution reactions. Its role in creating aromatic derivatives underscores its importance in the chemical industry and academic research in Indonesia.
TCI brochures (PDF)
- Nucleic Acid Medicine Synthesis Research Reagents 2024-11-07 · p. 2
- Protecting Agents 2025-03-25 · p. 7
- Nucleosides, Nucleotides, Nucleic Acids and Related Reagents 2026-03-23 · p. 13
- Reagents for Glyco Chemistry & Biology 5th Edition · p. 129
- Organic synthesis of aromatic compounds due to its electrophilic nature and reactivity in nucleophilic substitution reactions.
- Preparation of carboxylic acids and esters through hydrolysis and esterification processes.
- Synthesis of heterocyclic compounds as a key intermediate in ring-forming reactions.
- Halogenation reactions where Benzoyl Chloride serves as a source of the acyl group.
- Development of pharmaceutical compounds in research settings requiring functional group transformations.
| Brand | TCI |
|---|---|
| CAS number | 98-88-4 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Non-Heterocyclic Building Blocks |
| Pack sizes | Available in standard laboratory quantities |
| Physical form | Liquid |
| Storage | Store in a cool, dry place away from moisture and light |
Benzoyl Chloride should be stored in a cool, dry environment, away from moisture and direct light. It is recommended to keep it in a tightly sealed container made of materials resistant to chemical corrosion, such as glass or polyethylene. Due to its corrosive and toxic properties, it must be handled in a well-ventilated area, preferably under a fume hood. Personal protective equipment, including gloves, goggles, and a lab coat, should always be worn when working with this compound. It is important to avoid skin contact and inhalation, and to follow standard safety protocols for handling reactive chemicals in the laboratory. Proper disposal methods should also be followed to ensure environmental safety.
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