N-(tert-Butoxycarbonyl)-L-proline TCI B1188

Chemical Identity

Other names: Boc-Pro-OH
CAS No.: 15761-39-4
PubChem: CID 85083·SID 87564125
Formula: C10H17NO4
Molecular weight: 215.25 g/mol
Purity: >99.0%(T)
Reference databases: ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
SMILES: CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O
InChIKey: ZQEBQGAAWMOMAI-ZETCQYMHSA-N

Rp 557.550,00

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N-(tert-Butoxycarbonyl)-L-proline is a chemical compound widely used in organic and biochemical applications, particularly in peptide synthesis. As a protected amino acid, it plays a crucial role in the construction of complex molecular structures within laboratory settings. Its utility spans across various research fields, including pharmacology, biotechnology, and medicinal chemistry, where precise molecular design is essential. This compound is commonly employed in the development of synthetic proteins and bioactive molecules, making it an indispensable tool for researchers aiming to create novel therapeutic agents.

The chemical properties of N-(tert-Butoxycarbonyl)-L-proline make it a preferred choice for peptide synthesis due to its stability and reactivity. The tert-butyloxycarbonyl (Boc) group provides a reliable protective mechanism, allowing for controlled deprotection under specific conditions. This characteristic ensures that the amino acid can be selectively modified without unwanted side reactions. Its compatibility with various synthetic protocols further enhances its appeal in laboratory environments where precision and reproducibility are paramount.

In Indonesian laboratories, N-(tert-Butoxycarbonyl)-L-proline is frequently used in drug development, protein modification, and the synthesis of biomedically relevant compounds. Researchers across academic institutions and research organizations rely on this compound for experiments requiring high precision and quality materials. Its stability and reactivity make it a key component in advancing biochemical research and innovation in the region.

TCI brochures (PDF)

Amino Acids and Peptide Synthesis Reagents 2025-08-14 · p. 12

Related TCI products

Peptide Synthesis: This compound is ideal for constructing peptide sequences due to its stable Boc protection and controlled deprotection properties.
Drug Development: It is used in the synthesis of bioactive molecules, supporting the creation of novel therapeutic agents.
Protein Modification: Its role in protecting amino acid residues allows for precise modifications in protein engineering applications.
Medicinal Chemistry Research: The compound is essential for designing and synthesizing compounds with pharmaceutical relevance.
Biochemical Analysis: It contributes to the study of molecular interactions and structural biology in research settings.

Brand	TCI
CAS number	15761-39-4
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes	Available in various quantities as per standard laboratory supply
Physical form	Solid powder
Storage	Store in a cool, dry place away from moisture and direct sunlight

N-(tert-Butoxycarbonyl)-L-proline should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep the compound in a sealed container to prevent moisture absorption, which could affect its integrity. Avoid exposure to direct sunlight and high humidity, as these conditions may lead to degradation. In laboratory settings, it is important to handle the compound with care, using appropriate personal protective equipment such as gloves and safety goggles. Proper labeling and storage in a designated chemical storage area will ensure safe handling and minimize the risk of contamination or accidental exposure.

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