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Bicyclo[1.1.1]pentan-1-amine Hydrochloride (CAS 22287-35-0) is a high-quality chemical from TCI, supplied as GC Grade / for Synthesis.
Application: Synthesis reagent for a wide range of organic chemistry transformations in laboratory and industrial settings.
Specifications:
- Molecular formula: C5H9N.HCl
- CAS number: 22287-35-0
- Purity: >98.0%(GC)(T)
- TCI product code: B5479
Available from AMI Scientific, the authorised TCI distributor in Indonesia. Contact us for pricing and stock availability — we ship throughout Indonesia.
Advantages (TCI brochure)
- Bicyclo[1.1.1]pentane is a bioisostere of benzene rings
- Adds sp3 carbon character, expected to improve solubility
- Increases 3-dimensionality of drug candidates
TCI brochures (PDF)
- Building Blocks for Bioisosteric Replacement in Medicinal Chemistry 2026-01-05 · p. 1
- Bicycloalkane Building Blocks ― Benzene Bioisosteres ― 2025-04-01 · p. 1
Related TCI products
- TCI B6523 1638767-25-5 tert-Butyl (3-Aminobicyclo[1.1.1]pentan-1-yl)carbamate
- TCI D6184 303752-38-7 3-[(tert-Butoxycarbonyl)amino]bicyclo[1.1.1]pentane-1-carboxylic Acid
- TCI M3149 83249-10-9 3-(Methoxycarbonyl)bicyclo[111]pentane-1-carboxylic Acid
- TCI D6351 115913-32-1 Dimethyl Bicyclo[1.1.1]pentane-1,3-dicarboxylate
- TCI B6619 22287-28-1 Bicyclo[1.1.1]pentane-1-carboxylic Acid
- TCI B6609 1050886-56-0 4-[(tert-Butoxycarbonyl)amino]bicyclo[2.1.1]hexane-1-carboxylic Acid
From the TCI brochure
- Bioisosteric replacement of benzene rings in medicinal chemistry
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References cited in the TCI brochure
- Murugaiah A. M. Subbaiah. Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design Journal of Medicinal Chemistry, 2021. doi:10.1021/acs.jmedchem.1c01215
Product Categories
- Building BlocksNon-Heterocyclic Building BlocksNitrogen Compounds [Non-Heterocyclic Building Blocks]
- Building BlocksSpecialized Building Blocks for Drug DiscoveryBicyclo[1.1.1]pentane Building Blocks
- Pharmaceutical Development and Drug Discovery Research ReagentsSpecialized Building Blocks for Drug DiscoveryBicyclo[1.1.1]pentane Building Blocks
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