TCI B6523, tert-Butyl (3-Aminobicyclo[1.1.1]pentan-1-yl)carbamate (CAS 1638767-25-5), is a mono-Boc-protected bicyclo[1.1.1]pentane diamine widely used as a rigid, three-dimensional building block in medicinal chemistry. The BCP core serves as a well-known bioisostere of the benzene ring, allowing researchers to explore saturated alternatives to aromatic scaffolds. Its free amine can be selectively functionalised while the Boc-protected nitrogen remains masked until acidic deprotection is required. AMI Scientific supplies this reagent in original TCI packaging in 100 mg and 500 mg sizes for discovery-scale research.
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- Chmovzh et al. (2021). tert-Butyl Bis(4′-(Hexyloxy)-[1,1′-biphenyl]-4-yl)carbamate. Molbank doi:10.3390/m1247
- (2009). MILD AND EFFICIENT ONE-POT CURTIUS REARRANGEMENT: PREPARATION OF N-tert-BUTYL ADAMANTANYL-1-YL-CARBAMATE. Organic Syntheses doi:10.15227/orgsyn.086.0113
- (2022). Diasterocontrol Synthesis of Tamiflu Intermediate of Tert- butyl(5-hydroxy-6-(1-ethylpropoxy)-1,2-epoxycyclohex- 3-en-1-yl)carbamate. MALAYSIAN JOURNAL OF CHEMISTRY doi:10.55373/mjchem.v24i2.258
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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