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TCI

CAS 29166-72-1

2-tert-Butyl-1,1,3,3-tetramethylguanidine TCI B6052

2-tert-Butyl-1,1,3,3-tetramethylguanidine TCI B6052
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Description

2-tert-Butyl-1,1,3,3-tetramethylguanidine (CAS 29166-72-1), commonly known as Barton's base, is a sterically hindered, strong, non-nucleophilic guanidine base widely employed in organic synthesis. Its primary applications include selective deprotonation, elimination reactions, and serving as a base in coupling and condensation reactions where nucleophilic interference must be avoided. This TCI-grade reagent is available in 1 g and 5 g packaging, making it suitable for both small-scale exploratory research and routine synthetic workflows.

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