TCI B6460 4'-tert-Butylacetophenone (CAS 943-27-1) is an aromatic ketone supplied as a versatile non-heterocyclic building block. Its carbonyl group supports reduction, aldol condensation, and enolate alkylation, and it is frequently used as a model substrate in asymmetric catalysis studies. The 4-tert-butylphenyl motif is common in medicinal chemistry, agrochemical, and fragrance-related intermediates. Handle it with appropriate protective equipment in a well-ventilated area and store it tightly closed in a cool, dry place away from heat and oxidizers.
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- BAKHVALOV (1993). ChemInform Abstract: Nitration of 2,6‐Dimethyl‐4‐tert‐butylacetophenone.. ChemInform doi:10.1002/chin.199344138
- Avakyan et al. (2026). Sensitized Room-Temperature Phosphorescence of Phenanthrene in the Phenanthrene–β-Cyclodextrin–4'-tert-Butylacetophenone Complex. High Energy Chemistry doi:10.1134/s0018143926700268
- Api et al. (2018). RIFM fragrance ingredient safety assessment, p-tert-butylacetophenone, CAS Registry Number 943-27-1. Food and Chemical Toxicology doi:10.1016/j.fct.2018.07.039
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